Properties
Description
Lentinan-angiopep, referenced as angiopep-lentinan, engineers a blood-brain barrier-targeting conjugate through LDL receptor-binding peptide attachment to lentinan's glucan framework. This CNS-penetrating derivative preserves triple-helix architecture while enabling brain tumor suppression via thymic activation.
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
Angiopep
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-angiopep can be used for its potential to develop phosphatidylserine-PEG conjugates for apoptotic cell mimicry in immune evasion research.
