Properties
Description
Lentinan-poly(lactic-co-glycolic acid), termed PLGA-lentinan, constitutes a contemporary biochemical hybrid merging the immune-regulatory β-1,3-1,6-glucan lentinan with PLGA. The hybrid compound utilizes lentinan's triple-coil configuration and cancer-restraining potential via thymus-dependent immunological stimulation pathways.
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-poly(lactic-co-glycolic acid) can be used for its potential to explore PLGA blends for sustained antigen release in vaccine adjuvant longevity studies.
