Properties
Description
Lentinan-poly-ornithine, identified as poly-ornithine-lentinan, forms a cationic polymer conjugate through attachment of polyamino acids to lentinan's glucan framework. The charge-modified hybrid preserves triple-helix geometry while enhancing nucleic acid delivery for thymic immune potentiation against tumors.
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
Poly-ornithine
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-poly-ornithine can be used for its potential to stabilize polyplex structures with poly-ornithine coatings for improved gene transfection efficiency.
