Properties
Description
Lentinan-poly-sarcosine, denoted poly-sarcosine-lentinan, constructs a stealth polymer conjugate through N-methyl glycine attachment to lentinan's β-1,3-1,6-glucan framework. The PEG-mimetic hybrid preserves triple-helix conformation while prolonging circulation time for sustained thymic immune activation.
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
Poly-sarcosine
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-poly-sarcosine can be used for its potential to create stealth coatings with poly-sarcosine modifications to evade immune cell recognition.
