Properties
Description
Lentinan-R8 peptide, termed R8-lentinan, creates a polyarginine-conjugated variant by bonding octa-arginine sequences to lentinan's β-1,3-1,6-glucan chains. This cell-penetrating derivative sustains helical structure while improving cellular uptake of immunotherapeutic signals via thymus-dependent mechanisms.
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-R8 peptide can be used for its potential to enhance cell-penetrating capabilities through R8 peptide conjugation in nuclear delivery studies.
