Properties
Description
Lentinan-transferrin, referred to as transferrin-lentinan, represents a newly developed conjugate combining the immunomodulatory β-1,3-1,6-glucan lentinan with transferrin. This synthesized design leverages lentinan's helical tertiary architecture and anti-tumor attributes through thymic-mediated immune response activation processes.
Glycan Structure
Its glycan structure is a β-(1→3)-linked d-glucose backbone with β-(1→6)-glucosyl side branches.
Source
Chemical synthesis
Functional Group
Transferrin
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Lentinan-transferrin can be used for its potential to design transferrin-coupled systems for receptor-mediated transcytosis across endothelial barriers.