Properties
Description
Xylan-tretinoin bioconjugation strategically couples the retinoid's cellular signaling capacity with xylan's β-1,4-xylose polysaccharide structure, utilizing the carbohydrate scaffold's hydrophilic nature to overcome intrinsic solubility limitations of hydrophobic agents.
Glycan Structure
Its glycan structure is a linear backbone of β-1,4-linked D-xylose residues with side-chain substitutions including α-linked arabinofuranose, glucuronic acid/4-O-methyl-glucuronic acid, and acetyl groups at O-2 or O-3 positions.
Source
Chemical synthesis
Functional Group
Tretinoin
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Xylan-tretinoin can be used for its potential to investigate retinoid receptor activation in cellular differentiation assays.
