Artificial Intelligence-assisted Glycan-related Drug Discovery Service
CD BioGlyco is at the leading edge of glycan-related research and development, using advanced artificial intelligence (AI) to accelerate drug discovery. With our extensive expertise in glycobiology and professional team, we offer comprehensive AI-assisted glycan-related drug discovery services to address the unique needs of researchers and pharmaceutical companies.
Drive Innovation and Achieve Breakthroughs in the Development of Novel Glycan-targeted Therapies
AI-assisted glycan-related drug discovery uses machine learning (ML) and deep learning (DL) techniques to analyze complex glycan data, this is a service that predicts interactions between glycans and potential drug candidates. By combining advanced computational tools with our extensive expertise in glycan biology, we offer innovative solutions for target identification, biomarker discovery, small molecule design, and high-throughput virtual screening.

- At this early step, we combine different datasets to create comprehensive models including glycan structures, glycoprotein interactions, and biological activities.
- Then, we use AI to identify patterns and relationships in glycan-related data that may be missed by traditional methods.
- Next, we develop algorithms to predict how glycans interact with drug and biological targets and optimize the design of glycan-targeted therapies.
- At this step, we evaluate large numbers of compounds quickly and efficiently using virtual screening techniques.
- In the last step, we iteratively refine drug candidates through predictive modeling and experimental validation to improve efficacy and reduce side effects.
Here are our AI-assisted glycan drug discovery services which are not limited.
Publication
DOI: 10.3390/ijms23158725
Technology: AI, high-throughput screening (HTS), disease models, and proteostasis regulators
Journal: International Journal of Molecular Sciences
IF: 5.6
Published: 2022
Results: The study identifies promising drug repositioning candidates for congenital disorders of glycosylation (CDG). Epalrestat improved metabolic and neurological symptoms in a single PMM2-CDG patient trial. Palovarotene reduced bone tumors in a mouse model of EXT1/EXT2-CDG and is now in clinical trials. Acetazolamide showed neurological improvements in PMM2-CDG patients in a phase 2 trial. Celastrol increased enzyme activity in PMM2-CDG cell models. These results highlight the potential of repurposed drugs, supported by AI, to enhance CDG treatment.
Fig.1 Repositioned drugs for CDG with modified chemical structures in clinical pipelines. (A) acetazolamide, (B) epalrestat, (C) palovarotene, and (D) celastrol. (Brasil, et al.,2022)
Frequently Asked Questions (FAQ)
- What is glycan-related drug discovery?
- Glycans are complex carbohydrates that play critical roles in various biological processes, including cell-cell communication, immune response, and protein stability and function. The field of glycan-related drug discovery focuses on understanding these roles and leveraging this knowledge to develop drugs that can modulate glycan functions for therapeutic purposes.
- What are the main advantages of using AI in glycan-related drug discovery?
- The main advantages include faster identification of potential drug candidates, more accurate predictions of drug efficacy and safety, and the ability to explore a broader chemical space than traditional methods. This leads to more efficient drug development pipelines and potentially lower costs.
Applications
- AI algorithms can identify and validate glycan-related targets associated with cancer, enabling the development of targeted therapies.
- AI can be used to identify glycan targets for vaccine development against pathogens like bacteria and viruses.
- AI can be used to identify glycan biomarkers for neurological diseases such as Alzheimer's and Parkinson's for early diagnosis and monitoring.
Why Choose CD BioGlyco?

- We utilize AI and ML algorithms to enhance the efficiency and accuracy of glycan-related drug discovery.
- Our team of experienced scientists and researchers specializes in glycoscience, ensuring high-quality service and insightful analysis.
- From target identification to drug design and optimization, we offer a full spectrum of services to support your research needs.
- We provide tailored solutions to meet the specific requirements of your research projects and drug development goals.
- We employ the latest advancements in computational pathology, molecular simulation, and virtual screening to drive innovative drug discovery.
Partnering with CD BioGlyco provides you with access to AI-assisted glycan-related drug discovery services, enhancing your research capabilities and accelerating your path to groundbreaking discoveries and therapeutic advancements. Please feel free to contact us for more information about the tools and support for your research and development goals.
Reference
- Brasil, S.; et al. Systematic review: drug repositioning for congenital disorders of glycosylation (CDG). International Journal of Molecular Sciences. 2022, 23(15): 8725.
For research use only. Not intended for any diagnostic use.
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