Glycoinformatics-assisted Glycogenomics Analysis Service
Unlock the Future of Glycogenomics with Glycoinformatics
Glycogenomics is the study of the synthesis, modification, function, and regulation of glycan molecules, like glycans and glycoconjugates, at the genomic level. It integrates the knowledge and techniques of genomics and glycobiology. At CD BioGlyco, we utilize our in-depth expertise and experience in
Glycoinformatics-assisted Glycomics Analysis to provide you with a trustworthy glycoinformatics-assisted glycogenomics analysis service.
Glycosyltransferase analysis and functional genomics
Our experts help clients with the investigation of glycosyltransferases through the application of glycoinformatics. Our experts assist in identifying genes that encode glycosyltransferases and glycosyl hydrolases, as well as annotating the functions of these enzymes through sequence alignment and analysis of functional domains. The evolutionary process and family expansion examination of these enzymes are also included in our service.
Advanced glycomics and genomics analysis
CD BioGlyco possesses our own glycomics and genomic databases, housing a wealth of glycoconjugate structures, functional annotations, metabolic pathways, experimental data, gene sequences, annotation information, and expression data. Additionally, our team of experts integrate external databases to provide you with comprehensive data support. Our experts utilize gene knockout, overexpression, and database assistance to investigate the specific roles of targeted genes in glycan chain synthesis and function.
Integrated glycogenomics and glycoinformatics analysis
In addition, we provide clients with the glycogenomics analysis and interpretation of glycomics data assisted by glycoinformatics. Using advanced glycoinformatics tools and databases, our experts annotate and categorize glycomics data to help you understand the meaning and function of your glycomics data. For example, we predict and annotate the functions of glycosyltransferases and glycosyl hydrolases in glycomics data based on glycoinformatics, which helps you to reveal glycan synthesis and degradation pathways in glycomics data.
Publication
Technology: Glycoinformatics
Journal: Asian Pacific Journal of Health Sciences
IF: 2.5
Published: 2021
Results: This article discusses the role of glycoinformatics in biomedical research. Glycoinformatics is a branch of bioinformatics that focuses on the study of different sugar chain structures and their roles in the organism. To make the role of glycoinformatics more systematic, researchers use various databases to study different diseases. The authors note that glycoinformatics can reveal the functions and regulatory mechanisms of key genes in the glycan synthesis and degradation pathways by analyzing the sequence and structural information of these genes. In addition, glycoinformatics can predict the functions and interactions of metabolites and enzymes in the glycan synthesis and degradation pathways by analyzing their structural information. In disease research, glycoinformatics help researchers identify genetic mutations associated with diseases of glycometabolism and predict the effects of these mutations on glycan synthesis and degradation pathways. This can help understand the mechanisms of disease and provide new ideas for disease research.
Applications
- Glycoinformatics-assisted glycogenomics analysis is used by researchers to identify specific glycosylation biomarkers associated with disease.
- Glycoinformatics-assisted glycogenomics analysis can be used to optimize the metabolic pathways of industrial microorganisms for the efficient production of target products.
- Researchers use glycoinformatics-assisted glycogenomics analysis to analyze the the glycosylation genome of the individual to understand the impact of different genotypes on nutrient requirements and metabolism, which in turn guide individualized dietary recommendations for health promotion and disease prevention.
Fig.1 Demonstration of merging different databases to advance research in functional glycobiology. (Li, et al., 2020)
Advantages
- We combine the techniques and methods of glycomics and genomics to provide a comprehensive and integrated analysis of the interactions between glycosylation and the genome, leading to an in-depth understanding of the interrelationship between glycosylation and the genome.
- Our technology handles large-scale high-throughput data, including genome sequences, transcriptome data, and structural and functional information of glycosylated biomolecules, providing clientd with a rich data resource.
- We use a combination of knowledge and techniques from bioinformatics, computational biology, molecular biology, and other subject areas to provide you with more comprehensive analysis results.
Frequently Asked Questions
- What is glycoinformatics?
- Glycoinformatics is a discipline that studies the structure, metabolism, function, and interaction with other biomolecules of sugar molecules. The study of glycoinformatics includes structural analysis of sugar moieties, functional analysis of glycosylation modifications, and biosynthetic pathways of sugar molecules.
- What types of studies is this technology suitable for?
- This technology applies to the study of glycan synthesis, degradation, regulation, and any process related to genomics in organisms. It can be applied to the study of glycometabolic pathways, glycan signaling, glycosylation modifications, and regulation of glycan and gene expression.
CD BioGlyco is confident that our glycoinformatics-assisted glycogenomics analysis service will significantly enhance the progress of your research. Our dedication to quality goes beyond simply providing accurate data. If you are interested in more details, please feel free to contact us.
References
- Malhotra, R. Role of glycoinformatics in biomedical research: a review. Asian Pacific Journal of Health Sciences. 2021, 8: 113-116.
- Li, X.; et al. Databases and bioinformatic tools for glycobiology and glycoproteomics. International Journal of Molecular Sciences. 2020, 21(18): 6727.
For research use only. Not intended for any diagnostic use.
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