Glycan Data Interpretation, Integration and Visualization

Glycan Data Interpretation, Integration and Visualization

Unraveling the Mysteries of Glycans Through Comprehensive Analysis

Glycans have regulatory functions in their own right and are also involved in protein folding and degradation. Interpretation, integration, and visualization of glycan data are essential to studying glycans. At CD BioGlyco, we provide a comprehensive glycan data visualization service. Our glycan data interpretation, integration, and visualization help gain meaningful insights into glycan data to advance research and scientific understanding in glycobiology.

We provide a variety of means to analyze glycans, such as nuclear magnetic resonance (NMR) and high-performance liquid chromatography (HPLC), and to visualize glycan data. Our team seeks diverse and efficient glycan visualization solutions to meet our clients' glycan-related research. Through comprehensive and rapid analysis, we help understand glycan diversity and structure-function relationships at multiple levels, including glycan-protein interactions, gene expression, etc.

Our comprehensive glycan visualization services. (CD BioGlyco)

We are proficient in the characteristics of various analytical tools and develop an appropriate analytical process for the ultimate research purpose. Our glycan data visualization services include the following two main areas:

Assay

We have a variety of techniques for the overall analysis of glycans, including HPLC, capillary electrophoresis, NMR, microarrays, and so on. According to the specific research purpose of our clients, we develop a detailed analysis plan and carry out the relevant assays.

Glycan data visualization

Improvements in experimental analysis methods lead to a significant increase in the amount of glycan data generated. Various databases and tools are used to store, retrieve, and analyze glycan data. Based on our extensive experience in Analysis and Prediction, glycan data (composition, spatial structure, etc.) are integrated, processed, and visualized using various bioinformatics tools.

  • Glycan data captured from chromatography, mass spectrometry, electrophoresis, glycan arrays, and other experiments are visualized based on a variety of flexible and highly available tools.
  • We also visualize glycopeptide composition data to help complete glycopeptide analysis.
  • In addition to this, we also visualize glycan 3D structure, glycan structure lig-plot, and glycan interaction.

To better meet the needs of our clients, we also provide them with the following more detailed options for glycan data visualization services.

These services apply to biomarker discovery, pathways, genomics, disease studies, etc. We tailor protocols and perform accurate and comprehensive analyses based on our client's research needs.

Publication Data

Technology: Glycan data integration analysis

Journal: Scientific Reports

IF: 4.6

Published: 2022

Results: Glycans are potential disease biomarkers. In this study, N-glycans from multiple patients were analyzed by HPLC, and the resulting glycan data were analyzed in an integrated manner, which provided methodological support for the visualization of glycan data.

Fig.1 A complete process for glycan analysis.Fig.1 Flow chart of N-glycan data analysis for each sample. (Adua, et al., 2022)

Frequently Asked Questions

  • How can glycan data be used to analyze interactions between glycoproteins?
    Glycan data visualization provides insight into the glycan structure of glycoproteins and analyzes the binding preferences of glycoproteins to elucidate potential interactions between glycoproteins.
  • How is the visualization of glycan data important for cancer research?
    Abnormalities in glycan structure are associated with cancer development and progression. By comparing the differences between the glycans of cancer samples and healthy samples, it is possible to gain insight into the mechanisms of cancer development and progression, as well as to screen for potential cancer biomarkers.

Applications

  • Glycan biomarker discovery: By analyzing the differences in glycans between different control and disease groups, potential glycan biomarkers can be screened for, among other things.
  • Pathway analysis: Visualization of glycan data provides rich information for analyzing cellular processes, etc.
  • Glycogene expression analysis: Visualization of glycan data provides useful information for studying and predicting glycogene expression, glycan structure in specific cells, etc.

Our Highlights

  • Expertise: Our team consists of highly skilled experts with a deep understanding of glycans.
  • Customized solutions: We tailor our solutions to the specific needs of our clients to effectively analyze and interpret glycan data.
  • Timely delivery: Our team delivers results within the agreed timeframe, ensuring that our clients move forward with their research quickly.

CD BioGlyco provides an efficient glycan data visualization service to ensure your research goals are met. We maintain constant communication throughout the project. Please feel free to contact us for more details.

Reference

  1. Adua, E.; et al. Multi-block data integration analysis for identifying and validating targeted N-glycans as biomarkers for type II diabetes mellitus. Scientific Reports. 2022, 12(1): 10974.
For research use only. Not intended for any diagnostic use.
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We envision a future where the intricate world of carbohydrate is no longer shrouded in mystery, but rather illuminated by the power of cutting-edge computational tools.

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