Glycan Composition Data Interpretation, Integration and Visualization

Glycan Composition Data Interpretation, Integration and Visualization

Unparalleled Glycan Composition Data Integration Meets Cutting-Edge Visualization

Glycans are more complex biomolecules than nucleoids and proteins, so it is challenging to comprehensively define a format to store and present molecular information. The complexity of glycans lies mainly in the molecules, post-translational modifications, and building block collections. Moreover, information about glycosidic linkage, residue modifications, and substitutions also needs to be considered. CD BioGlyco has professional computational staff to provide high-quality Glycoinformatics-assisted Analysis/Prediction. Our lab provides personalized Glycan Data Visualization according to the client's needs.

Glycan composition data analysis

Our researchers use advanced analytical tools to help our clients interpret, integrate, and visualize glycan composition data. Our tools support manual input or automated import of experimental masses (average masses or single isotopes) to be analyzed. Our computational tools provide services for screening all possible compositions of a glycan structure from its experimentally determined mass.

Based on the sequence or mass of the peptide provided by the client, we offer a compositional calculation service for a glycan attached to the peptide.

The same mass corresponds to many glycan compositions. Our experienced staff provides output composition constraint services. We provide output rationalization based on known oligosaccharide structure constraints on monosaccharide composition.

Glycan composition data visualization

Our goal is to simplify your glycan composition data analysis process. Starting with data file extraction, our powerful calculation tools reorganize, filter, and import data to ensure consistency and ease of use. Our advanced calculation tools support fast and reliable transformations and searches, simplifying your entire management process.

Our lab provides intuitive data visualization. Clients quickly understand experiments and results with our specialized interactive views. Our computational tools support custom visualization to display specific parameters and conditions.

Flowchart of glycan composition data visualization. (CD BioGlyco)

Publication

Technology: Glycome graph visualization and interpretation

Journal: Molecular & Cellular Proteomics

Published: 2020

IF: 5.232

Results: In this work, the researchers introduce a new software tool for glycan composition visualization and comparison. Through a shared database and glycan characterization, the tool outputs interactive maps of glycan information. Moreover, the tool is designed to help users quickly select sample specifications for N- or cell line types and diseases including species, tissue, or cell line glycan composition.

Fig.1 Comparison of IgG N-glycome with two experimental datasets.Fig.1 Inferred N-Linked properties in two datasets. (Robin, et al., 2020)

Applications

  • Glycan composition data visualization can be used to predict the composition of glycoprotein-derived oligosaccharides, acetylated monosaccharides, or derived reducing ends.
  • Glycan composition data visualization can be used to analyze the composition of glycans attached to glycopeptides.
  • Glycan composition data visualization Can be used to quickly calculate the mass of glycoprotein-linked oligosaccharides.

Advantages of Us

  • Our computational tools are excellent for visualizing complex and large-scale data.
  • Our researchers consider the effects of post-translational modifications (including acetylation, methylation, sulfation, and addition of individual OGlcNAc residues) on data analysis.
  • The computational tools we offer with a scalable range of applications such as requesting additional functionality or integration to meet unique experimental needs.

Frequently Asked Questions

  • What are some common data visualization formats?
    • Common data visualization formats include frequency tables, crosstabs, bar graphs, line graphs, pie charts, scatter plots, and heat maps.
  • What makes our visualization tool unique?
    • Our comprehensive data preprocessing system features powerful data storage space and simultaneous online analysis capabilities. Our functional areas with intuitive and clear visualization provide easy access to our customers.

CD BioGlyco has rich experience in glycan composition data visualization. Whether you want to add new visualization areas, integrate unique glycan features, or customize your data display, our calculation system meets all your needs. Please feel free to contact us.

Reference

  1. Robin, T.; et al. Examining and fine-tuning the selection of glycan compositions with GlyConnect Compozitor. Molecular & Cellular Proteomics. 2020, 19(10): 1602-1618.
For research use only. Not intended for any diagnostic use.
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We envision a future where the intricate world of carbohydrate is no longer shrouded in mystery, but rather illuminated by the power of cutting-edge computational tools.

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