Whether it is liquid chromatography (LC), gas chromatography (GC), or other chromatography is an effective technique for analyzing glycans. Due to the complexity of chromatographic fingerprint information, manually analyzing the data one by one is a very time-consuming task. With the development of glyco-bioinformatics, the Analysis and Prediction accuracy of glycan-related data are increasingly higher. Our reliable Glycan Data Visualization team provides advanced algorithms and reliable staff to help clients efficiently process large volumes of glycan chromatography data. CD BioGlyco seamlessly integrates different data using already trained models to simplify coordination and ease management.
Relying on huge datasets and experimental data provided by our clients, we provide data classification, model construction, training, and peak collation services. Our common datasets include a training set, a stop set, and a validation set.
Our researchers use deep learning to select network structures and train convolutional neural networks. We focus extraordinarily on chromatography data management and optimization. Pre-training patterns are iteratively practiced to achieve the highest level of prediction.
Our researchers use computational software to visualize, process, and analyze the large amounts of complex, multidimensional data generated by chromatography. We provide basic data interpretation including data preprocessing, peak detection, and identification.
Our high-quality technicians provide visualization and analysis of two-dimensional chromatography data. Based on computer visualization techniques, our calculators use color and time dimensions to emphasize the visual communication of chromatographic features.
Our professional computing team supports one-stop data visualization solutions based on the client's data characteristics including data organization, advanced model design, model optimization, visual presentation, free switching of peaks, custom area, etc.
Technology: Automatic time-shift alignment method (ATSA), GC coupled with a flame ionization detector (FID), Correlation optimized warping (COW), Dynamic time warping
Journal: Scientific Reports
Published: 2017
IF: 3.8
Results: In this work, the researchers describe a new method, ATSA, for complex chromatographic data processing. The method uses peak information to automatically optimize manually dependent parameter settings such as fragment size, retention time, chromatographic peak area, etc. Moreover, the researchers tested the method and found that the method simultaneously processes the data, correct for background drift and time-shift alignment.
Fig.1 Detailed difference between COW and ATSA in the aligned chromatograms. (Zheng, et al., 2017)
CD BioGlyco has high-precision and high-quality chromatography data visualization tools to drive our clients' projects. Our researchers have extensive backgrounds in biology and computer science to meet our clients' needs. Please feel free to contact us.
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We envision a future where the intricate world of carbohydrate is no longer shrouded in mystery, but rather illuminated by the power of cutting-edge computational tools.