Aciclovir and Glucose Injection Analysis Service

Aciclovir and Glucose Injection Analysis Service

Client Satisfaction with Aciclovir and Glucose Injection Analysis Service Is Our Motivation

CD BioGlyco offers analysis services for many types of Pharmaceuticals such as Amikacin, Erythromycin Lactobionate, Saccharated Pepsin, aciclovir, and glucose injection, etc. Aciclovir and glucose injection is a combination of aciclovir (a nucleoside antiviral substance) and glucose in a sterilized aqueous solution used in the research of herpes virus, etc. We offer a one-stop aciclovir and glucose injection analysis service to support our clients in their pharmacokinetic studies, etc. We design analytical protocols for specific purposes according to client requirements based on our extensive experience in Pharmaceutical and Biological Analysis and state-of-the-art systems. All our analytical methods are validated for accuracy and precision. Aciclovir and glucose injection-related analytical programs are listed below.

  • Character observation: The sample should be a colorless or almost colorless clear liquid.
  • Sample identification:
    • We add an alkaline copper tartrate test solution to the sample and then observe whether there is red precipitation.
    • We observe whether the retention time of the main peak in the chromatogram is consistent with that of the control by high-performance liquid chromatography (HPLC).
  • pH value: The pH value of the sample should be 3.5~5.5.
  • Guanine and other related substances: The content of guanine and impurities in the sample is detected by HPLC.
  • 5-Hydroxymethylfurfural: The content of 5-hydroxymethylfurfural in the sample is detected by HPLC. The amount of 5-hydroxymethylfurfural should not be more than 0.03% of the labeled amount of glucose.
  • Determination of content:
    • Aciclovir: We detect the content of aciclovir contained in the sample by HPLC.
    • Glucose: We detect the optical rotation of the sample and calculate the amount of glucose in the sample.
  • Other tests: Microbiological tests, bacterial endotoxins, heavy metals, molar concentration of osmolality, etc.

Fig.1 Aciclovir and glucose injection analysis service. (CD BioGlyco)Fig.1 Aciclovir and glucose injection analysis service. (CD BioGlyco)

Publication Data

Technology: HPLC

Journal: AAPS PharmSciTech

IF: 2.451

Published: 2016

Results: In the present study, the researchers analyzed the stability of parenteral acyclovir when diluted in dextrose as a high-volume intravenous liquid formulation by HPLC and other methods. The results showed that when acyclovir was diluted in glucose solution, the level of drug loss ranged from 0.27% to 1.03% of its initial content. This study demonstrates the suitability of HPLC for the correlation analysis of acyclovir.

Fig.2 Mass spectra of acyclovir under different treatment conditions.Fig.2 Mass spectra of acyclovir under different treatment conditions. (Siahi Shadbad, et al., 2016)

Advantages of Us

  • We have many years of expertise in bioanalytical method development and pharmaceutical analysis.
  • We combine a variety of rapid, highly sensitive assays to efficiently analyze aciclovir and glucose injection, including aciclovir quantification, impurity quantification, heavy metal detection, etc.
  • Our optimized solutions for the analysis of aciclovir and glucose injection allow us to produce rapid results and shorten project delivery times.

CD BioGlyco has developed analytical techniques to meet the needs for the analysis of a wide range of pharmaceutical products such as aciclovir and glucose injection. Please feel free to contact us with the purpose of your experiment if you need aciclovir and glucose injection analysis. Our project manager will contact you as soon as possible to communicate with you.


  1. Siahi Shadbad, M.R.; et al. Investigation of possible maillard reaction between acyclovir and dextrose upon dilution prior to parenteral administration. AAPS PharmSciTech. 2016, 17: 1491-1499.
This service is for Research Use Only, not intended for any clinical use.

About Us

CD BioGlyco is a world-class biotechnology company with offices in many countries. Our products and services provide a viable option to what is otherwise available.

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