GlycoNano™ Platform

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Overview of Glyconanoparticle

Glycoparticles are intricate molecules characterized by their glycosylated surfaces. These unique particles play pivotal roles in numerous biological processes, including cell communication, immune response, and pathogen recognition. Our glycoparticles are meticulously engineered to offer vast potential for therapeutic applications, targeted drug delivery, and enhanced biocompatibility in medical devices.

Unlock Innovation with GlycoNano™ Platform

At CD BioGlyco, our GlycoNano™ platform is dedicated to advancing the frontier of glyconanotechnology. We offer a range of comprehensive services, from the development and characterization of glyconanoparticles to their application in preclinical studies. Our platform also focuses on the development of homogeneous glyconanohydrogels and biosensors based on nanotechnology, providing key support for the next generation of biomedical research and applications. In addition, our GlycoNano™ bioink production service provides revolutionary material solutions for 3D printing technology.

Glyconanoparticle Development Service

Our glyconanoparticle development service offers a suite of cutting-edge Glyconanoparticle Production Techniques tailored for creating sophisticated glycoparticles. Leveraging Hydrogen Bonding, Coulombic Interactions, and Hydrophobic Effects, we craft glycoparticles with precise structural control. Additionally, our expertise in CuAAC, Amide Coupling, Nucleophilic Substitution, and Photocoupling enables the synthesis of glycoparticles with diverse functionalities and biological activities. In addition to the following glycoanoparticles, we also provide Carbon-based Glyconanoparticle, Fluorescent Glyconanoparticle, Silica Glyconanoparticle, and Liposome Glyconanoparticle Production Service.

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Carbohydrate-based Nanoparticle

Magnetic Glyconanoparticle

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Gold Glyconanoparticle

Quantum Dot (QD) Glyconanoparticle

Glycol Nanohydrogel Development Service

We specialize in glycol nanohydrogel development services, employing cutting-edge Glycol Nanohydrogel Production Techniques such as Precipitation Polymerization, Inverse Emulsion Polymerization, and Microtemplate-assisted Polymerization. Our portfolio also includes advanced services based on Precipitation/Crosslinking, Emulsion/Crosslinking, Self-assembly/Crosslinking, and Microtemplating/Crosslinking. These methodologies enable the precise tailoring of glycol nanohydrogels, catering to diverse research and industrial needs.

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In addition to glyconanoparticle and glycol nanohydrogels, we also provide Glycol Nanorod, Glycol Nanotube, and Glycol Nanocrystal/Nanosheet/Nanosphere/Nanofiber Production Service.

After successfully producing nanomaterials, we transition seamlessly into the characterization phase. Here, we introduce our Glyconanoparticle Characterization Service, which encompasses physicochemical property characterization and molecule interaction analysis. through these comprehensive evaluations, we gain in-depth knowledge of nanomaterial stability, surface properties, and interaction dynamics with other molecules.

Glyconanoparticle Physicochemical Property Characterization

Elemental Analyzer HIC XPS FTIR NMR
RS SPR TGA Morphology SANS

Glyconanoparticle Molecule Interaction Analysis Service

FCA DSL ITC Super-microarray FRET SPR
Carbo-Carbo
Interaction		 Carbo-Protein
Interaction		 Carbo-Lipid
Interaction		 Carbo-Polyphenol
Interaction		 Carbo-Nucleic acid
Interaction		 Multi-molecule
Interaction

Glyconanoparticle Preclinical Study Service

Our expertise lies in meticulously designing and executing preclinical trials to evaluate the safety, efficacy, and biodistribution of glyconanoparticles. With cutting-edge facilities and a dedicated team of scientists, we ensure comprehensive data analysis and regulatory compliance, accelerating your research journey from lab to market. Trust us for reliable, insightful preclinical insights.

(CD BioGlyco)

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Glyconanoparticle Formulation Service

We offer comprehensive glyconanoparticle formulation services. Our portfolio includes drug loaded, biological agent loaded, diagnostic agent loaded, nutrient loaded, cosmetic ingredient load, and agricultural chemical loaded glyconanoparticle formulations. Tailored to your specific needs, our expert team ensures optimal encapsulation, stability, and delivery. With advanced technology and rigorous testing, we deliver innovative solutions for your research and development endeavors.

(CD BioGlyco)

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Glyconanotechnology-based Biosensor Development Service

Our service leverages the unique properties of glyconanoparticles to create highly sensitive and specific biosensors. From design to prototyping, our team ensures precision and reliability, tailored to your application needs. With cutting-edge technology and expertise, we accelerate your biosensor development journey.

We also offer GlycoNano™ Bioink Production Service for 3D Printing. Our GlycoNano™ Carbohydrate Base Material Bioink ensures precise control over glycosylation patterns. For tissue-specific applications, our GlycoNano™ Tissue-specific Bioink caters to the unique requirements of various tissues. Both services harness the power of glyconanotechnology to revolutionize 3D bioprinting.

Applications of Glyconanoparticles

  • Glyconanoparticle can be used in the development of biosensors for disease detection.
  • Glyconanoparticle can be used to enhance vaccine efficacy by improving immune cell interaction.
  • Glyconanoparticle can be used in the study of glycoprotein interactions and functions.

Advantages

  • Enhanced Targeted Delivery: Our glyconanoparticle platform can be used to develop highly targeted delivery systems.
  • Versatile and Customizable: Our platform allows for the creation of glyconanoparticles tailored to specific applications, offering a versatile solution for a wide range of research needs.
  • Improved Biocompatibility: Our glyconanoparticle platform offers enhanced biocompatibility, reducing the risk of adverse reactions and improving patient tolerance to treatments.

Publication

Published: 2015

Journal: Polymer Chemistry

IF: 5.4

Results: The article discusses the advancement of glyconanoparticles, which are nanoparticles functionalized with carbohydrates, and their interactions with carbohydrate-binding proteins known as lectins. These particles are playing a pivotal role in nanobiotechnology, particularly in the fields of drug delivery, biosensing, and pathogen detection, due to their ability to mimic natural glycan structures. The paper delves into the synthesis and properties of different types of glyconanoparticles, including those with metal cores and polymer shells, and examines their multivalent interactions with lectins to establish highly specific binding, akin to natural systems.

Fig.1 Preparation of gold nanoparticles coated by polymers.Fig.1 Synthesis of polymer-coated gold nanoparticle. (Yilmaz, et al., 2015)

Frequently Asked Questions

  • What are the key benefits of using a glyconanoparticle platform for my research or therapeutic development?
    A glyconanoparticle platform offers numerous benefits, including enhanced targeted delivery of therapeutic agents, improved biocompatibility, and the ability to incorporate imaging agents for real-time monitoring. This platform enables the creation of highly customizable nanoparticles that can be tailored to specific applications, addressing unique challenges in drug delivery, imaging, and more.
  • Can the glyconanoparticle platform be customized to fit the specific requirements of my research or therapeutic application?
    Absolutely. Our platform allows for the creation of glyconanoparticles tailored to specific applications. Whether you need a nanoparticle with a particular size, shape, or surface chemistry, or one that targets a specific cell type or tissue, our team of experts work with you to develop a custom solution that meets your unique needs.

At CD BioGlyco, our glyconanoparticle platform specializes in the precise engineering of glycoparticles for advanced biomedical applications, leveraging innovative nanotechnology to tailor glycosylated surfaces for enhanced cell targeting, drug delivery, and immune modulation. With customizable features and robust performance, it offers unparalleled versatility. We invite customers to contact us to explore collaboration opportunities and harness the full potential of our groundbreaking platform.

Reference

  1. Yilmaz, G.; Becer, C. R. Glyconanoparticles and their interactions with lectins. Polymer Chemistry. 2015, 6(31): 5503-5514.
This service is for Research Use Only, not intended for any clinical use.
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Hydrogen Bonding-based Glyconanoparticle Development Service
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Coulombic Interaction-based Glyconanoparticle Development Service
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Monosaccharide-based Nanoparticle Production Service
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Polysaccharides-modified Nanoparticle Production Service
Resources
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Precise analysis for Decoding Disease Proteins
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Your Advanced Glycan Synthesis Solution
Platforms
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Featured Products
Nucleic Acid Drug Delivery Products
GalNAc-L96 intermediate, T1 (Cat#: X24-11-YM010) GalNAc-L96 intermediate, T2 (Cat#: X24-11-YM011) GalNAc-L96 intermediate, T3 (Cat#: X24-11-YM012) GalNAc-L96 intermediate, T4-Amine (Cat#: X24-11-YM014) Tri-GalNAc(OAc)3 Cbz (Cat#: X24-11-YM015) Tri-GalNAc(OAc)3 (Cat#: X24-11-YM016) Tri-GalNAc(OAc)3 TFA (Cat#: X24-11-YM017) GalNAc-L96-OH (Cat#: X24-11-YM018) GalNAc-L96-TEA (Cat#: X24-11-YM019)
Hots Products
N-Glycan
Neu5Gcα(2-6)N-Glycan (Cat#: X23-03-YW036) A2G2 N-Glycan (Cat#: X23-03-YW037) A2G2S2 N-Glycan (Cat#: X23-03-YW038) A2 N-Glycan (Cat#: X23-03-YW039) A2[6]G1 N-Glycan (Cat#: X23-03-YW040) M3 N-Glycan (Cat#: X23-03-YW041) A2[3]G2S1 N-Glycan (Cat#: X23-03-YW042)
O-Glycan
Core 2 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW178) Core 2 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW179) Core 3 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW180) Core 3 O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW181) Core 4 O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW182) T antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW192) T antigen O-glycan, Thr-Fmoc linked (Cat#: X23-10-YW193) Tn antigen O-glycan, Ser-Fmoc linked (Cat#: X23-10-YW194)
Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
Glycosaminoglycans
Heparin amine, MW 27 kDa (Cat#: X22-09-ZQ478) FITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ480) TRITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ481) Biotin-heparin-FITC, MW 18 kDa (Cat#: X22-09-ZQ482) Chondroitin sulfate (dp4) (Cat#: X22-11-ZQ598) Dermatan sulfate (dp12) (Cat#: X22-11-ZQ611) Heparin disaccharide I-A (Cat#: X22-11-ZQ662) Chondroitine sulfate (Cat#: X23-04-XQ1118)
Carbohydrate Conjugates
GalNAcβ(1-4)GlcNAcβ-Sp3-Biotin (Cat#: X22-12-ZQ005) GalNAcβ(1-4)GlcNAcβ-Sp3-PAA-Biotin (Cat#: X22-12-ZQ006) GalNAcβ(1-4)GlcNAcβ-Sp3-PAA-FITC (Cat#: X22-12-ZQ007) GalNAcβ(1-4)GlcNAcβ-Sp3-PAA (Cat#: X22-12-ZQ008) Glcβ(1-4)GalNAcα-Sp3-Biotin (Cat#: X22-12-ZQ037) Glcβ(1-4)GalNAcα-Sp3-PAA-Biotin (Cat#: X22-12-ZQ038) Glcβ(1-4)GalNAcα-Sp3-PAA-FITC (Cat#: X22-12-ZQ039) Glcβ(1-4)GalNAcα-Sp3-PAA (Cat#: X22-12-ZQ040)
Glycolipids
GlcCer (d18:1/8:0) (Cat#: X23-11-ZQ101) GalCer (d18:1/16:0) (Cat#: X23-11-ZQ112) LacCer (d18:1/8:0) (Cat#: X23-11-ZQ118) Lc3Cer (d18:1/8:0) (Cat#: X23-11-ZQ131) Lc4Cer (d18:1/12:0) (Cat#: X23-11-ZQ146) Sialyl-Lc4Cer (d18:1/18:0) (Cat#: X23-11-ZQ162) Lewis a Cer (d18:1/16:0) (Cat#: X23-11-ZQ175) nLc4Cer (d18:1/18:0) (Cat#: X23-11-ZQ190)
Cyclodextrin
Methyl-γ-cyclodextrin (DS 12) (Cat#: X23-11-YM119) Carboxymethyl-ɑ-cyclodextrin sodium salt (Cat#: X23-11-B003) Carboxymethyl-γ-cyclodextrin sodium salt (Cat#: X23-11-B004) Succinyl-ɑ-cyclodextrin (Cat#: X23-11-B005) Succinyl-γ-cyclodextrin (Cat#: X23-11-B006) ɑ-Cyclodextrin sulfate sodium salt (Cat#: X23-11-B007) β-Cyclodextrin sulfate sodium salt (Cat#: X23-11-B008) γ-Cyclodextrin sulfate sodium salt (Cat#: X23-11-B009)
Dextran
Lysine-dextran, MW 4 kDa (Cat#: X22-09-ZQ273) Phenyl-dextran, MW 150 kDa (Cat#: X22-09-ZQ279) FITC-Q-dextran, MW 10 kDa (Cat#: X22-09-ZQ280) FITC-lysine-dextran, MW 10 kDa (Cat#: X22-09-ZQ283) TRITC-lysine-dextran, MW 10 kDa (Cat#: X22-09-ZQ287) FITC-dextran sulfate, MW 10 kDa (Cat#: X22-09-ZQ291) Dextran amine, MW 20 kDa (Cat#: X22-09-ZQ377) TRITC-dextran, MW 40 kDa (Cat#: X22-09-ZQ383) Biotin-dextran-FITC, MW 20 kDa (Cat#: X22-09-ZQ389)
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