Phytosterols are getting more and more attention in the fields of medicine, food, and life sciences. CD BioGlyco provides sterols quantitative analysis services in different samples by gas chromatography (GC), liquid chromatography (LC), and gas chromatography-mass spectrometry (GC-MS).
Sterol is an alcohol compound with cyclopentane perhydrophenanthrene (steroid nucleus) as the skeleton. It mainly exists in animals and plants in the form of free sterols, sterol glycosides, sterol fatty acids, fatty acyl sterol glycosides, and sterol hydroxyaromatic acid esters. The C-5 position of most sterols is a double bond. The C-3 hydroxyl is one of the important active groups, through which sterols form various derivatives. There are many types of sterols. According to different sources, they are divided into three categories: animal sterols, fungal sterols, and plant sterols. Animal sterols are mainly cholesterol, which is mainly found in the blood, fat, brain, and nerve tissues of humans and animals; Fungal sterols mainly include ergosterol and fucosterol, which are mainly found in molds and mushrooms; Phytosterols mainly include β-sitosterol, stigmasterol, campesterol, and rapeseed sterol. The structure of plant sterols is similar to that of animal sterols. The only difference is the difference in the number of methyl groups attached to position C-4 and the difference in the side chain at position C-11. It is the slight differences in these side chains that make their different physiological functions.
Phytosterols and their derivatives have important physiological functions, such as reducing blood cholesterol concentration, preventing and curing prostate diseases, as anti-cancer substances, hormone-like functions, and anti-inflammatory effects, and are widely used in food, feed, cosmetics, textiles, and other fields. As a component of the cell membrane, cholesterol plays an important role in regulating cell membrane fluidity, phase change and permeability, forming lipid rafts and micro-domains on the membrane.
Fig.1 The main pathways of plant sterols in the human body. (Kopylov, 2021)
Phytosterols have the effects of lowering blood cholesterol concentration, anti-cancer, anti-oxidation, anti-inflammatory, and antipyretic effects, etc., and are receiving more and more attention in the fields of medicine and life sciences, especially in the food industry. Therefore, it is necessary to conduct qualitative and quantitative analyses of sterols. At CD BioGlyco, the sterol analysis services we provide include but are not limited to:
Whenever you need a solution for cholesterol lipid analysis, we will work closely with you to determine the research purpose and develop a customized plan.
CD BioGlyco provides high-quality sterol analysis services for our clients worldwide. If you are interested in our services, please feel free to contact us.