Galactomannan is a polysaccharide containing a mannose backbone with a galactose side group, or more precisely, galactomannan is a polysaccharide with a linear (1-4)-linked β-D mannose backbone structure based on a 6-linkage to α-D galactose, i.e., a 1-6-linked α-D galactopyranose. Some plants and fungi contain components of galactomannans. The presence of galactomannan in human blood can be used to diagnose the presence of invasive Aspergillus molds in the human body. In clinical trials, galactomannan is effective in lowering blood glucose levels after meals.
Fig.1 Structural formula of galactomannan. (CD BioGlyco)
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Fig.2 Galactomannan analysis services. (CD BioGlyco)
Paper Title: Isolation and characterization of galactomannan from seed of Leucaena leucocephala
Journal: Polymer Bulletin
Results: The authors determined the molecular weights of galactomannans using the GPC technique. Specifically, an ultrahydrogel 2000 column was used to pass dextran standards with molecular weights of 12-270 kDa and the corresponding spectra were plotted as the logarithm of elution time versus the respective molecular weights. The results are shown in Fig.3. The molecular weight of galactomannan was inferred to be 6.4 × 104 Da based on the calibration curve of the dextran standard.
Fig.3 GPC chromatogram of pure galactomannan. (Rahim, et al., 2017)
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