Etimicin Sulfate Analysis Service

Etimicin Sulfate Analysis Service

Get the Facts Straight with Etimicin Sulfate Analysis Service

CD BioGlyco has the world's leading technology for the analysis of Pharmaceutical and Biological, providing comprehensive and reliable Pharmaceutical Analysis Services to clients around the world. Etimicin sulfate is a semi-synthetic aminoglycoside modified from gentamicin C1a and is an effective antibiotic against both gram-positive and gram-negative bacterial infections. At CD BioGlyco, we provide high-quality etimicin sulfate analysis services.

  • Identification of etimicin sulfate
    Thin layer chromatography (TLC): The sample to be tested and the standard are spread on the same silica gel thin layer chromatographic plate using an organic solvent as the spreading agent. Finally, the plate is placed in iodine vapor for color development and the positions of the colors are compared.
  • Analysis of etimicin sulfate
    • Acidity: Dissolve the sample to be tested with water and make a solution of a specific concentration. It is then tested using a pH meter.
    • Structure: We offer nuclear magnetic resonance (NMR), infrared spectroscopy (IR), and mass spectrometry (MS) methods to test the detailed structure of etimicin sulfate.
    • Molecular weight: We offer gel permeation chromatography (GPC) and MS to test the molecular weight of etimicin sulfate.
    • Heavy metal content: Etimicin sulfate samples are prepared into solution and then tested for heavy metal content using atomic absorption spectrometry (AAS) and atomic fluorescence spectrometry (AFS).
    • Content analysis: The etimicin sulfate sample is weighed precisely and diluted by adding a mobile phase. The sample solution and the control product are injected into the liquid chromatograph separately, and the peak areas in the chromatogram are calculated using the external standard method to obtain the content of etimicin sulfate in the sample.
    • Others

In addition, there are two main states of etimicin sulfate that will be analyzed.

  • Etimicin sulfate injection: Sterilized aqueous solution of etimicin sulfate is a clear colorless to slightly yellow or slightly yellowish-green liquid.
  • Etimicin sulfate for injection: Sterile lyophilized form of etimicin sulfate is a white or off-white powder or loose mass.

Similarly, we offer content determination, pH determination, and other analysis services on both of these substances.

Certainly, besides the above analysis services, we also offer other types of etimicin analysis according to the needs of our clients.

Fig.1 Etimicin sulfate analysis services. (CD BioGlyco)Fig.1 Etimicin sulfate analysis services. (CD BioGlyco)

Publication Data

Technology: LC coupled with pulsed electrochemical detection analysis

Journal: Journal of Separation Science

IF: 3.1

Published: 2016

Results: In this paper, the authors describe an improved LC method combined with pulsed electrochemical detection of etimicin sulfate. In this method, 22 impurities were able to be separated. In addition, the authors researched the effect of different chromatographic parameters on the separation results. For example, a fourfold potential-time waveform was applied to the electrodes of the detection unit; 0.8 M sodium hydroxide was added after the column, and the pH before detection was increased to at least 12. For the detection of etimicin sulfate, the authors also used a centralized composite design of experiments to characterize the relationship between the factors and the response values and to set up a factorial analysis. The improved method was shown to have higher sensitivity, better separation, and robustness.


  • We have top-notch drug analysis technology and provide custom analysis solutions, and systematic analysis reports to our clients.
  • Our service team consists of experts in the field to ensure the quality and efficiency of our analysis services.
  • We have timely pre-sales and after-sales services to ensure that our clients are informed of the progress of their projects.

CD BioGlyco has extensive experience in pharmaceutical analysis and provides quality pharmaceutical and biological services to our clients. We hope to be your right-hand man in the field of pharmaceutical analysis. If you are interested in our services, please feel free to contact us.


  1. Wu, Y.N.; et al. Improved liquid chromatography combined with pulsed electrochemical detection for the analysis of etimicin sulfate. Journal of Separation Science. 2016, 39: 1471-1479.
This service is for Research Use Only, not intended for any clinical use.

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