Professional databases and well-trained researchers are essential to conducting the glyco-gene microarray assay. Our huge probe library and advanced algorithm programs provide professional and reliable assistance for customers' glyco-gene microarray assay. CD BioGlyco has confidence to be your essential research assistant in the field of glycobiology.

Background

DNA microarray technology is similar to traditional Southern hybridization, Northern hybridization and other technologies. They are all developed based on the complementary characteristics of nucleic acids, and the hybridization between complementary single strands of nucleotides. But whereas conventional techniques can only analyze individual genes, microarrays have evolved as a high-throughput model. Researchers can use gene chips to quantitatively analyze the expression levels of a large number of genes at the same time, with rapid, accurate, and low-cost capabilities.

Compared with traditional methods for studying the differential expression of genes, it has the advantages of miniaturization, high sensitivity, and simultaneous large-information parallel detection on the same chip. The glyco-gene microarray is a focused oligonucleotide microarray containing all the cloned glyco-genes. It is a high-level technology for screening and detecting changes in the transcription and expression levels of glycan-related genes (such as glycan binding protein, glycosyltransferase, glycosylhydrolase, carbohydrate transporter, etc.). The glyco-gene microarray technologies currently on the market are based on Affymetrix technology.

Services

We provide the glyco-gene microarray assay developed using Affymetrix technology. It contains a large number of probes, which can monitor the expression of a variety of human and mouse transcripts, and can also be customized. Our customers only need to provide test samples to receive the one-stop service. The general process is as follows:

• Samples preparation
• Microarray fabrication, validation, and quality control
• Target preparation; RNA extraction and labeling, and microarray hybridization
• Data acquisition and statistical analysis
• Quantitated by high resolution confocal laser scanner

Applications

• Study genetic factors of disease risk and drug response 
• Precision medicine research
• Glyco-gene expression profiling
• Tumor detection

Advantages of Us

• Comprehensive genome-wide association analysis (GWAS) and clinical research marker coverage
• Dedicated algorithm program
• High precision and sensitivity
• One-stop service

CD BioGlyco has provided reliable and cost-effective research services to customers all over the world, and our considerate service and professional technology in the field of glycobiology have won us a great deal of praise.

Customers can contact our employees directly and we will respond promptly. If you are interested in our services, please contact us for more detailed information.

Reference:

1. Comelli, E. M.; et al. A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology. 2006, 16(2): 117-131.