During the occurrence and development of malignant tumors, cancer cells must obtain nutrients necessary for rapid growth, and at the same time need to escape the surveillance of the immune system. The important feature of glucose metabolism in cancer cells is aerobic glycolysis. The lactic acid produced through the glycolysis pathway reduces the pH value in the tumor microenvironment, and immune cells are inhibited by the acidic environment, resulting in the immune escape of cancer cells. The close link between tumor glucose metabolism reprogramming and tumor immune escape is thus seen. CD BioGlyco can analyze the relationship between tumor glucose metabolism reprogramming and immune escape to provide the impetus for the development of cancer immunotherapy.
Immune cells and cancer cells are co-located in the tumor microenvironment, and the competition for glucose metabolism between the two, as well as the glucose metabolites of cancer cells, can affect the induction of immune escape. If you want to further understand the crosstalk relationship between cancer glucose metabolism and tumor microenvironment, please click to go to the details page.
Reprogramming of glucose metabolism is not limited to cancer cells, but can also occur in immune cells. Immune cells and cancer cells compete for glucose uptake, and the imbalance of glucose metabolism will weaken the function of effector T cells, resulting in the immune escape of cancer cells.
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CD BioGlyco can analyze the relationship between cancer cell glucose metabolism reprogramming and immune escape, and the relationship between immune cell glucose metabolism reprogramming and immune escape. Our experienced teams of scientists, researchers, and technicians provide a fast turnaround, and high-quality services at competitive prices for worldwide customers. Our customers have direct access to our staff and prompt feedback on their inquiries. If you are interested in our services, please contact us for more details.