During the occurrence and development of malignant tumors, cancer cells must obtain nutrients necessary for rapid growth, and at the same time need to escape the surveillance of the immune system. The important feature of glucose metabolism in cancer cells is aerobic glycolysis. The lactic acid produced through the glycolysis pathway reduces the pH value in the tumor microenvironment, and immune cells are inhibited by the acidic environment, resulting in the immune escape of cancer cells. The close link between tumor glucose metabolism reprogramming and tumor immune escape is thus seen. CD BioGlyco can analyze the relationship between tumor glucose metabolism reprogramming and immune escape to provide the impetus for the development of cancer immunotherapy.

What We Do

• Analysis of the relationship between the glucose metabolism reprogramming and the tumor microenvironment

Immune cells and cancer cells are co-located in the tumor microenvironment, and the competition for glucose metabolism between the two, as well as the glucose metabolites of cancer cells, can affect the induction of immune escape. If you want to further understand the crosstalk relationship between cancer glucose metabolism and tumor microenvironment, please click to go to the details page.

• Analysis of the impact of immune cell glucose metabolism reprogramming on immunotherapy

Reprogramming of glucose metabolism is not limited to cancer cells, but can also occur in immune cells. Immune cells and cancer cells compete for glucose uptake, and the imbalance of glucose metabolism will weaken the function of effector T cells, resulting in the immune escape of cancer cells.

We can provide the following specific services based on the MOPCGM platform, including but not limited to:

• Analysis of the effect of glucose metabolism reprogramming in tumor cells on effector T cell activity
• Analysis of the effects of glucose metabolites on immune cell differentiation, metabolism and function

Our Advantages

• We are able to provide analytical services for the characteristicsa of immune cell glucose metabolism.
• We treat cancer cells and immune cells as a whole, and can comprehensively analyze the impact of glucose metabolism reprogramming on the effect of immunotherapy.

Applications

• Development of a comprehensive treatment strategy for immunotherapy combined with glucose metabolism-targeted therapy.
• The search for cancer treatments that inhibit cancer cells while maintaining immune cell activity.

CD BioGlyco can analyze the relationship between cancer cell glucose metabolism reprogramming and immune escape, and the relationship between immune cell glucose metabolism reprogramming and immune escape. Our experienced teams of scientists, researchers, and technicians provide a fast turnaround, and high-quality services at competitive prices for worldwide customers. Our customers have direct access to our staff and prompt feedback on their inquiries. If you are interested in our services, please contact us for more details.