CD BioGlyco has developed an advanced one-stop solution for lipidomics analysis. We are committed to providing clients with high-quality analysis services for ceramide, cerebroside, diglycosylceramide, globoside, ganglioside, sulfoglycosphingolipid, and phosphosphingolipid.
Sphingolipid is a class of amphoteric lipids containing a sphingosine backbone that was discovered in brain extracts in the 1870s. It generally exists in plant and animal membranes, especially in the tissues of the central nervous system. Phosphosphingolipid is a sphingolipid consisting of a ceramide backbone attached to a phosphorylated "head" group, found in animals, plants, bacteria, and fungi. Here, we will introduce 5 phosphosphingolipids.
Fig.1 Sphingolipid metabolic pathways in yeast and mammals. (Matmati & Hannun, 2008)
Due to the important functional and biological significance of phosphosphingolipid, it is highly necessary to develop rapid and accurate analytical techniques.
Mass spectrometry (MS) is increasingly used in lipidomic analysis. At CD BioGlyco, we have developed a high-sensitivity, reproducible, high-resolution, and high-accuracy method for sphingolipid analysis. We provide global clients with analysis services for SM, CPE, IPC, MIPC, and M(IP)2C in different samples by Q Exactive Orbitrap-MS. We will define the content of SM, CPE, IPC, MIPC, and M(IP)2C in pmol and mol%. After the project is completed, we will provide a complete project report, including sample preparation, analytical methods, instrument parameters, analytical data, and spectrum.
|Phosphosphingolipid||SM||Q Exactive Orbitrap-MS||
|CPE||Q Exactive Orbitrap-MS||
|IPC||Q Exactive Orbitrap-MS||
|MIPC||Q Exactive Orbitrap-MS||
|M(IP)2C||Q Exactive Orbitrap-MS||
CD BioGlyco has extensive experience in lipidomics and has developed various methods for lipid analysis. We are willing to share our knowledge and experience in this field. If you are interested in our services, please contact us for more details.