With more and more in-depth research on the physiological activities of polysaccharides, carbohydrate-based glycomedicine development has become the research hotspot in many fields. As one of the good sources of natural polysaccharides, the plant-derived polysaccharide is one of the potential materials for developing glycomedicine. With the advanced carbohydrate-based glycomedicine development platform and rich experience, CD BioGlyco provides customized services for plant-derived carbohydrate-based glycomedicine development.
Growing understanding and deeper investigations of the importance of polysaccharides in life science are driving the development of polysaccharides for novel biomolecular applications. Carbohydrates play important roles in the recognition of substances on the cell surface and in the transduction of signals. Carbohydrates are involved closely in various diseases such as infection and cancer. For these reasons, increasing efforts have been made to conduct research for drug development, focusing on carbohydrates in the biological body.
Plant-derived polysaccharides commonly found in nature (starch, cellulose, mannan, xylan, gum, etc.) are playing an important role in the pharmaceutical field. Many plant glycans have broad physiological significance as signaling molecules. These executive molecules fine-tune strategic intra- and inter-cell communication, coordinate biological networks, and recognize the host versus foreign cells such as infectious agents or tissues from another organism in the case of organ transplantation. Therefore, glycans play key roles in health, suboptimal health, and illness, as they mediate temporal-spatial informed responses to hostile or benevolent changes in the intercellular space as well as sensing and interacting with the broader microcellular environment.
Fig.1 Glycomedicine: glycans and their potential roles in precision medicine. (Wang, 2022)
CD BioGlyco provides services for the isolation, purification, biological activity identification, and structural identification of plant-derived natural polysaccharides such as starch and cellulose. In particular, CD BioGlyco carries out etherification, selective oxidation, enzymatic, and graft copolymerization modification of plant polysaccharides such as cellulose and alginate. These are powerful methods for the construction of natural polysaccharides having tailored biological functions. These chemical/chemo-enzymatic functionalizations are used to develop various valuable medicinal properties of plant-based polysaccharides.
CD BioGlyco has advanced instrumentation platforms and expertise in glycoscience. In addition, our professional research teams allow us to provide you with high-quality services for the development of plant-derived carbohydrate-based glycomedicine. If you are interested in our services, please contact us for more details without any hesitation.