In vivo metabolism research is a necessary step to study the glucose metabolism of cancer cells. CD BioGlyco provides blood glucose measurement in mice, whole body 18F-FDG PET/CT, micro-PET/CT imaging, tissue hypoxia detection, hyperglycemic clamp, and hyper-insulinemic euglycemic clamp assays, mice energy consumption, and metabolic function evaluation test. All of our services strictly follow the guidelines for the use of laboratory animals, the guidelines for laboratory animal science, the guidelines for laboratory animal ethics, and the guidelines for laboratory animal economics. The breeding environment of experimental animals conforms to national standards, all researchers involved in the experiment have been trained as laboratory animal practitioners and have obtained practicing qualification certificates.
Fig. 1 Cancer glucose metabolism in vivo research services we can provide
We take the blood from the tail vein of the tumor-bearing mice and use a blood glucose meter to detect the blood glucose of the mice.
We inject 18F-FDG through the tail vein of tumor-bearing mice and observe changes in the distribution of 18F-FDG in mice from the first second to the first hour after injection. Micro-PET/CT Imaging is a high-resolution in vivo imaging technique. The tumor-bearing mice were anesthetized and scanned to study the tumor metabolic status of the mice.
We detect hypoxic tissue by immunological methods, and injected hypoxia probes into tumor-bearing mice by intravenous injection, intraperitoneal injection, or oral method, and then detect.
The hyperglycemic clamp technique can quantify glucose metabolism and β-cell response and is the gold standard for assessing insulin secretion. It can be used to study the relationship between tumors and diabetes.
Fig. 2 The workflow of cancer glucose metabolism In vivo analysis
CD BioGlyco provides comprehensive services in cancer glucose metabolism In vivo analysis. Our experienced teams of scientists, researchers, and technicians provide fast turnaround, high-quality services at competitive prices for worldwide customers. Our customers have direct access to our staff and prompt feedback on their inquiries. If you are interested in our services, please contact us for more details.