N-glycans are glycans attached to proteins. N-glycans are found in a variety of organisms, including animals, plants, and microorganisms, and are significant for protein folding, stability, function, and cellular recognition. They are also involved in various processes including inflammation, immune response, and cancer metastasis. Dysfunctional N-glycosylation has been associated with a range of diseases which include cancer, congenital glycosylation disorders, and neurodegenerative diseases. N-glycans have a variety of physical and chemical characteristics, such as water retention, viscosity, gelling properties, and stability, and are therefore often used as materials in medicine, cosmetics, food, and industry. For example, some N-glycans have biological activities such as antioxidant, immunomodulatory, anti-inflammatory, and antibacterial, which can be used in the preparation of nutraceuticals and drugs.
Fig.1 Workflow for high-throughput N-glycan screening. (Kinoshita, et al., 2021)
N-glycans play a variety of critical roles in biology, providing the basic functional and structural support for living organisms. Therefore, the research on N-glycans is important for understanding and diagnosing diseases as well as developing drugs. CD BioGlyco focuses on diverse research in the field of glycobiology, including glycan analysis. We strive to provide efficient and cost-effective high-throughput N-glycan screening services for our global clients. Our N-glycan screening services include but are not limited to those listed below:
Fig.2 Technologies for HTS of N-Glycan. (CD BioGlyco, 2023)
CD BioGlyco provides customized high-throughput N-glycan screening services based on a variety of methods. Our professional, timely, and efficient after-sales service has resulted in very high client satisfaction. If you are interested in our services, please contact us for more details.