Streptomycin Injection Analysis Service

Streptomycin Injection Analysis Service

Experience the Exceptional Streptomycin Injection Analysis

Streptomycin is a broad-spectrum antibiotic that can be used to inhibit a wide range of bacterial infections and is particularly effective in killing tuberculosis bacteria. Streptomycin is commonly administered via injection, allowing for both intramuscular and intravenous routes of administration. CD BioGlyco has extensive expertise in Pharmaceutical Analysis, delivering meticulous and tailored streptomycin injection analysis services to our esteemed clientele.

  • CD BioGlyco offers services to identify the main active and auxiliary ingredients in injectable solutions and determine the content and purity of streptomycin. This helps clients ensure that the drug is formulated correctly and that the ingredients meet the requirements. For instance, the quantification of streptomycin content and related impurities is accomplished through high-performance liquid chromatography (HPLC), while individual components are identified and characterized using gas chromatography-mass spectrometry (GC-MS). Additionally, infrared spectroscopy and ultraviolet spectroscopy, are employed to aid in determining the characteristic peaks of the samples based on specific circumstances.
  • We provide the sample stability evaluation service under different conditions, including the effects of temperature, light, oxidation, and other factors on the drug.
  • CD BioGlyco evaluates the solubility and dissolution of drugs in injectable solutions, and the solubility under the conditions and provides clients with scientific and reliable data support based on the experimental results. For different types and characteristics of drugs, we will consider many factors, such as molecular structure, crystalline transition, degree of ionization, etc., when evaluating their solubility in injection solutions.
  • Our microbial limit testing service is to assess the extent of microbial contamination in injectable solutions. This helps to confirm that the microbiological quality of the drug complies with the relevant standards.
  • We provide streptomycin injection pharmacological property evaluation services, including pharmacodynamics, pharmacokinetics, and toxicity to help clients determine the behavior and effects of the streptomycin.

Fig.1 Streptomycin injection analysis service. (CD BioGlyco)Fig.1 Streptomycin injection analysis service. (CD BioGlyco)

Publication Data

Technology: Liquid chromatography-tandem mass spectrometry (LC-MS/MS), Solid phase extraction (SPE), Ion electrospray (ESI)

Journal: Analytica Chimica Acta

IF: 6.2

Published: 2010

Results: This article describes a method for the determination of streptomycin in apples. The method utilized LC-MS/MS techniques and was validated according to SANCO/3131/2007. First, sample preparation was carried out by phosphate buffer extraction and pH change, followed by a clean-up using polymeric phase SPE. The LC-MS/MS analysis employed a hydrophilic exchange column to separate the analytes present in the samples, while a triple quadrupole MS was utilized to measure the conversion of substances in positive ESI mode. To quantify streptomycin, a calibration curve using matrix standards with a linear range spanning from 1.0 to 20 μg/kg was established, alongside an internal standard dihydrostreptomycin at a concentration of 10 μg/kg. The performance of the method was verified by calculating the recoveries (101-105%) and the relative standard deviations (RSDs, 4.1-11.4%) of six replicate samples. The quantification limit of this method was determined to be 2 μg/kg.

Fig.2 Chemical structure of streptomycin.Fig.2 Chemical structure of streptomycin. (Al-Ameri, et al., 2023)


  • We possess a comprehensive understanding of the intricate structural intricacies and wide-ranging variations exhibited by streptomycin as a natural product, enabling us to assist you in conducting a more sophisticated analysis.
  • Our company offers a diverse array of analytical techniques for streptomycin, encompassing chromatography, spectrometry, mass spectrometry, and other advanced technical methods. This enables you to select the most appropriate analytical approach based on your specific requirements.
  • Our advanced analytical technology allows for the precise and reliable detection of streptomycin, even at extremely low concentrations within the sample.

CD BioGlyco offers a comprehensive and efficient streptomycin injection analysis service, tailored to meet the detailed needs of our esteemed clients in drug development. If you need additional details about the services we offer, please feel free to contact us.


  1. Al-Ameri, S.A.H.; et al. Synthesis, characterization, and HPLC analysis of streptomycin with its derivatives. Journal of Pioneering Medical Sciences. 2023, 12(4).
  2. Bohm, D.A.; et al. Confirmatory method for the determination of streptomycin in apples by LC-MS/MS. Analytica chimica acta. 2010, 672(1-2): 103-106.
This service is for Research Use Only, not intended for any clinical use.

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