Lactose-based Biodegradable Material Development

Lactose-based Biodegradable Material Development

High-quality Lactose-based Material Development Service Win Clients' Trust

Based on an experienced team and well-established laboratory equipment, CD BioGlyco provides high-quality development services for Biodegradable Materials Based on Disaccharides. Lactose is a disaccharide composed of a glucose unit covalently bound to a galactose unit, which exists in the form of α- or β-heterodimers. It is rich in hydroxy functionality and ease of functionalization, making it attractive as a raw material for the preparation of hydrophilic materials. We provide a one-stop service for the development of lactose-based biodegradable materials including hydrogels.

  • Preparation of lactose-based biodegradable material development

Hydrogel is a hydrophilic polymer network. Incorporation of carbohydrates such as lactose into the polymer structure is a viable strategy to introduce hydrophilicity. We prepare lactose-based hydrogels by chemical cross-linking (formed by covalent bonding connections between polymer chains) or physical cross-linking (electrostatic interactions, strong hydrogen bonding, van der Waals interactions, etc.). After determining the experimental scheme, by modifying lactose or mixing it with other polymers, we prepare lactose-based hydrogels by click chemistry, photopolymerization reaction, etc. In the process of preparation, we regulate the mechanical properties, water absorption, and rheology of the resulting hydrogels by changing the ratio of lactose, etc.

In addition, we develop biodegradable materials such as lactose-based films for food packaging and drug delivery.

  • Analysis of lactose-based biodegradable materials

For specific biodegradable materials, we have a very comprehensive material analysis program. We analyze the chemical, biological, and physical properties of the material.

  • Physical properties: Search engine marketing (SEM) analysis, differential scanning calorimetry (DSC) analysis, X-ray diffraction analysis (XRD) analysis, etc.
  • Chemical properties: Nuclear magnetic resonance (NMR) analysis, Fourier-transform infrared spectroscopy (FTIR) analysis, etc.
  • Biological properties: Antimicrobial activity, biocompatibility, mechanical properties, biodegradability, etc.

Flowchart of lactose-based biodegradable material development.Fig.1 Flowchart of lactose-based biodegradable material development. (CD BioGlyco)

Publication Data

Technology: Photocrosslinking

Journal: ACS Sustainable Chemistry & Engineering

IF: 8.198

Published: 2020

Results: In this study, a lactose-based hydrogel was prepared using lactose from dairy industry waste. The lactose was derivatized with methacrylic anhydride (MAH), while methacrylate groups were added to the lactose. The lactose-based photopolymerization into a hydrogel was finally successfully synthesized by hydrogel photopolymerization reaction using methacrylic acid (and/or corresponding salt) as the copolymerizing monomer. The physical and chemical properties of the hydrogel were examined, and the results showed that the hydrogel had a good performance, and hydrogels with different properties could be prepared by changing the ratio of lactose and MAH.

Preparation of lactose-based hydrogels by photocrosslinking.Fig.2 Preparation of lactose-based hydrogels by photocrosslinking. (Fonseca, et al., 2020)


  • Lactose-based biodegradable materials have potential use in biomedical applications, such as the control and release of biologically active drugs.
  • Lactose-based biodegradable materials have potential use in food applications, e.g. as edible food packaging.
  • Lactose-based biodegradable materials have potential use in the development of personal hygiene products.

Highlights of Us

  • We provide integrated solutions for the development and production of biodegradable modified materials and products.
  • We prepare biodegradable materials with different mechanical properties, water absorption, rheology, and so on.
  • Guided by client needs, we send real-time experimental progress reports and analyze test data to our clients.

CD BioGlyco offers a one-stop solution for the development of carbohydrate-based biodegradable materials. Please feel free to contact us for more information on the development of lactose-based biodegradable materials. Please trust us, our quality and service never let our clients down.


  1. Fonseca, L.R.; et al. Atom-economical, one-pot, self-initiated photopolymerization of lactose methacrylate for biobased hydrogels. ACS Sustainable Chemistry & Engineering. 2020, 8(11): 4606-4613.
This service is for Research Use Only, not intended for any clinical use.

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CD BioGlyco is a world-class biotechnology company with offices in many countries. Our products and services provide a viable option to what is otherwise available.

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