Biological Significance of Galactose

Galactose is a monosaccharide and is often found in plant, animal, and microbial sugars. Galactose is an important structural molecule in hydroxyethylcellulose, which is an important component of plant cell walls, maintaining cell morphology, providing mechanical strength, and protecting plant cells. Galactose is also essential for human metabolism and has an important role in energy transfer and galactosylation of complex molecules. It serves as a sugar source for cellular metabolism for energy supply and metabolism after being synthesized. Galactose can be converted to glucose via metabolic pathways to provide energy to cells and can also be chemically covalently bound to proteins to form a specific glycosylation modification that has important effects on protein stability, structure, and function. Many studies have shown that galactose has also certain biological activities in pharmacology, for example, it has certain effects on the protection of cardiovascular vessels and against diseases such as diabetes.

Fig.1 Structure of galactose. (Wikipedia)

High-Throughput Screening (HTS) of GalactoseService at CD BioGlyco

As a provider of high-throughput glycan screening services, CD BioGlyco is dedicated to researching and developing advanced glycan analysis and screening services to help clients accelerate the development and production of glycan-related products. We offer a wide range of services and are not limited to those listed below:

• HTS of galactose by Microchip-Based Assay
  Microchip-based assay is suitable for different types of samples, such as serum, urine, animal tissues, etc., and the analysis process is fast, while the response is rapid, allowing for real-time detection.
• HTS of galactose by Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF-MS)
  MALDI-TOF-MS is capable of detecting very small molecules of galactose, allowing for rapid and accurate detection of the presence of galactose in samples.
• HTS of galactose by Electrospray Ionization Tandem Mass Spectrometry (ESI-MSn)
  ESI-MSn allows qualitative and quantitative analysis of substances with high sensitivity and accuracy.

Fig.2 Technologies for HTS of galactose. (CD BioGlyco)

Applications

• Discovery of functional components that promote or inhibit galactose metabolism
• Screening of potential drug molecules targeting galactose-related diseases or metabolic disorders
• Helps to screen microbial strains with high galactose-producing ability, thus improving the yield and efficiency of biologics

Advantages of Us

• Direct analysis of solution samples without the need for sample heating and vaporization
• High sensitivity and accuracy
• Complete after-sales solutions

CD BioGlyco has a professional team including several experienced glycochemists and biologists and advanced high-throughput galactose screening technologies to provide personalized and high-quality galactose HTS services for our clients. If you are interested in our services, please contact us for more details. We are eager to support you in your glycobiology research.