Unlocking the Power of Alpha Cyclodextrin Analysis

With the support of a professional Pharmaceutical and Biological Analysis team, CD BioGlyco provides our clients with satisfactory Pharmaceutical Excipient Analysis services. Moreover, we also provide high-quality Pharmaceutical Analysis and Biological Evaluation services. Cyclodextrin is a cyclic oligosaccharide linked by an alpha-1,4-glycosidic bond. We provide reliable analytical services for alpha cyclodextrin, beta cyclodextrin, and gamma cyclodextrin respectively.

• Basic analysis
  • Specific rotation
  • Impurity absorbance
  • Heavy metal

  • pH
  • Loss on drying
  • Solubility

  • Clarification
  • Residue on ignition
  • Microbial limit
• Identification
  • We mix the test samples with iodine solution and heat the water bath to dissolve it. After letting it cool, we observe whether a yellow-brown precipitate is produced.
  • We compare the plots of samples and standards by Fourier transform infrared (FTIR) and high-performance liquid chromatography (HPLC). Their liquid phase retention times and spectral characteristic peaks are analyzed one by one.
• Structural characterization
  • CD BioGlyco provides specialized alpha cyclodextrin structural analysis services through X-ray diffraction (XRD), scanning electron microscopy (SEM), low-frequency Raman spectroscopy, and differential scanning calorimetry (DSC).
• Quantitative analysis
  • Determination of reducing sugar content
    We dissolve alpha cyclodextrin and mix it with an alkaline copper tartrate test solution, then boil them to collect the precipitate. The precipitate is further dissolved with a hot ferric sulfate test solution, filtered, and washed. We titrate with potassium permanganate titrant and calculate the amount of reducing sugar in alpha cyclodextrin.
  • Determination of related substance content
    Dissolve and dilute the sample to be tested with water and then determine it by HPLC. Our professional researchers separate and identify each peak.
  • Determination of alpha cyclodextrin content
    We determine alpha cyclodextrin samples and standards by HPLC, respectively. The content is determined by peak area according to the external standard method.

Publication Data

Applications of Alpha Cyclodextrin Analysis

• Alpha cyclodextrin analysis to help improve drug bioavailability and efficacy.
• Comprehensive analysis of alpha cyclodextrin facilitates the development and design of novel drug delivery agents.
• Alpha cyclodextrin analysis plays a key role in the analysis of food additives.
• Analysis of alpha cyclodextrin in complexes can be used to reveal its mechanism of action in reaction kinetics and thermodynamics.

Advantages of Us

• Our talented team plans reliable pharmaceutical excipient analysis projects based on the client's needs to ensure high-quality delivery.
• All analytical conditions are pre-tested numerous times to ensure optimal results.
• We provide our clients with comprehensive analytical and qualitative reports including chromatographic separation conditions, optimization conditions, raw chromatograms, and analytical reports.

Based on professional analysis staff, CD BioGlyco provides clients with the most satisfied and assured pharmaceutical and biological analysis service. We look forward to being your first choice for pharmaceutical excipient analysis. Please feel free to contact us with any inquiries.