CD BioGlyco has accumulated extensive experience in the field of glycomedicine development. We customize systematic solutions according to customers' scientific research needs in glycomedicine development. We have the confidence to be your essential research assistant in the field of glycobiology.
With the deepening of our understanding of biology, recombinant proteins have become an important class of biological macromolecules that are widely used in medicine, industry, agriculture, environmental protection, and other fields. In the arena of medicine, therapeutic proteins, such as antibodies, cytokines/growth factors, and hormones, are indispensable for the prevention and treatment of cancer, infections, autoimmune diseases, metabolic genetic diseases, and many other diseases, largely due to their advantages of high specificity, low toxicity, and defined biological functions. They are now the fastest-growing segment of the global pharma market.
However, due to the nature of biological macromolecules, proteins also have their own problems. Because of their large molecular weight, complex composition and structure, many proteins have limited solubility and thermal and proteolytic stability. They can be denatured during storage or are prone to aggregation and chemical modifications, such as oxidation and deamidation. The existence of these problems can result in decreased efficacy of therapeutic proteins and increased immunogenic side effects. Glycoengineering is a method of improving the properties of proteins by changing their glycosylation.
Fig.1 Overview of mammalian N-glycosylation. (Dammen-Brower, et al.,2022)
CD BioGlyco has developed a highly specialized carbohydrate-based glycomedicine development platform and various systematic solutions for glycoengineered protein-based glycomedicine development. Our services include but are not limited to:
CD BioGlyco aspires to become the trusted solution provider of your first choice. Our advanced technologies and highly experienced staffs are committed to advancing your program and reducing the overall development timeline. Our professional research teams provide customers with high-quality glycoengineered protein-based glycomedicine development according to their needs. For further details, please don't hesitate to contact us.