Calcium Gluceptate Analysis Service

Calcium Gluceptate Analysis Service

High-level Analysis of Calcium Gluceptate in Different Forms

Calcium gluceptate (C14H26CaO16 (anhydrous)) is a highly water-soluble calcium salt with a wide range of applications. In solution, calcium is present in the form of free ionized or calcium glucoheptanoate complexes such as calcium glubionate syrup, and calcium gluceptate injection. Calcium gluconate is a solution containing equal amounts of calcium gluconate and calcium lactate or predominantly calcium lactate. Calcium gluconate injection is a sterile solution of calcium gluconate in water for injection. CD BioGlyco has an advanced analysis system to help our clients analyze calcium gluceptate quickly. We provide high-quality Pharmaceutical Analysis, Biological Evaluation services, and Pharmaceutical Excipient Analysis services.

Calcium Gluceptate Analysis Service at CD BioGlyco

  • Characterization
    CD BioGlyco characterizes the chemical structure, morphology, and elemental composition of calcium gluceptate by using Fourier-transform infrared (FT-IR) and scanning electron microscopy (SEM) analysis.
  • Identification
    • Calcium: Our researchers use direct titration to determine the calcium content in the solution and then calculate the percentage of calcium gluceptate (C14H26CaO16) in the sample.
    • Thin-layer chromatography (TLC): We provide TLC analysis services for standard solutions and sample solutions. Our analytical solution provides a range of services from solution preparation, plate preparation, development chamber preparation, ultraviolet (UV) detection, and data comparison.
    • Impurity analysis: We provide impurity identification services such as chlorides, sulfates, and reducing sugars analysis.
    • Others: We provide determination for pH and loss on drying. Besides, by analysis of thermal weight, the percentage of volatile substances is determined. We average all assay data several times to ensure the reliability of the data.
  • Special test
    • Bacterial endotoxins test (BET): We provide BET service through kinetic turbidimetric, kinetic chromogenic, or gel-clot tests. All tests are performed at least repeatedly. Positive product controls and negative controls are included as part of each test.
    • For the calcium gluconate injection, we provide a particulate matter analysis service.

Fig.1 Schematic diagram of Calcium gluceptate analysis service. (CD BioGlyco)Fig.1 Schematic diagram of calcium gluceptate analysis service. (CD BioGlyco)

Publication Data

Technology: FT-IR, SEM, Methyl thiazolyl tetrazolium (MTT) assay, Fluorescent cell imager, Western blotting, Immunofluorescence, Quantitative reverse transcriptase PCR (qRT-PCR) assay

Journal: PLoS One

Published: 2019

IF: 3.752

Results: In this work, researchers tested the effect of calcium glucoheptonate on the development and proliferation of osteoblast-like MG-63 cells in vitro by cellular and molecular biological methods. The multiplex analysis showed that the proliferation and calcium uptake of treated MG-63 cells increased. Meanwhile, the expression of bone-bridging proteins and osteogenic genes was increased in the treated cells. In addition, to detect the damage of calcium glucoheptonate on epithelial cells, researchers treated Caco-2 and human embryonic kidney 293T (HEK-293T) cells with calcium glucoheptonate, and no cytotoxic effects were detected.

Fig.2 Changes in the expression pattern in MG-63 cells treated with calcium glucoheptonate. (Modi, et al., 2019)Fig.2 Changes in the expression pattern in MG-63 cells treated with calcium glucoheptonate. (Modi, et al., 2019)

Advantages of Us

  • Our validation and method development service is effective and compliant.
  • We have a professional analysis team to help clients analyze data and provide fast and accurate data reports.
  • All solutions and data reports are delivered to clients.

With many years of experience, CD BioGlyco is happy to help clients with any issues regarding Pharmaceutical and Biological. Our company values every collaboration with clients and is committed to providing you with the perfect solution. Please feel free to contact us if you have additional questions about the calcium gluceptate analysis service.


  1. AHMED, N.H.; et al. Influence of calcium chloride on osteoblast like cells of both sexes in rats in in vitro conditions. Van Veterinary Journal. 2021, 32(3): 92-97..
  2. Modi, P.K.; et al. Effect of calcium glucoheptonate on proliferation and osteogenesis of osteoblast-like cells in vitro. PLoS One. 2019, 14(9): e0222240.
This service is for Research Use Only, not intended for any clinical use.

About Us

CD BioGlyco is a world-class biotechnology company with offices in many countries. Our products and services provide a viable option to what is otherwise available.

Contact Us

Copyright © CD BioGlyco. All rights reserved.