The metabolism of cancer cells is regulated by dynamic and complex networks. Metabolomics can only analyze static metabolites, while metabolic flux analysis techniques can describe the metabolic state of cancer cells at a dynamic level. Glycolysis is the process of decomposing one molecule of glucose into two molecules of pyruvate, and the flux analysis of glycolysis is to analyze the rate of this process and determine the direction of glucose metabolism in the process. CD BioGlyco uses isotope-labeled tracers for glycolytic metabolic flux analysis to grasp the metabolic status of the glycolytic pathway throughout cancer progression.
Metabolic flux analysis is the main research method of metabolic fluxomics, among which the metabolic flux analysis of glycolysis is more in the primary position in the study of glucose metabolism in cancer cells. We provide metabolic flux analysis of glycolytic pathways based on the MOPCGM platform.
We provide steady-state glycolytic metabolic flux analysis and non-steady-state glycolytic flux analysis. Among them, steady-state glycolytic flux analysis has an independent marker collection mode, which takes a long time. Non-steady-state glycolytic flux analysis takes less time but requires more time points to be analyzed. You can choose according to your needs.
For glycolytic flux analysis, the labeling methods we can provide are as follows:
The glycolytic metabolites we are able to label are as follows, including but not limited to:
|Glucose 6-Phosphate||Glucose 1-Phosphate|
|Fructose 6-Phosphate||Fructose 1,6-Bisphosphate|
|3-Phosphoglyceric Acid||2-Phosphoglyceric Acid|
|Phosphoenolpyruvic Acid||Pyridoxal 5-Phosphate|
CD BioGlyco can provide glycolytic metabolic flux analysis of cancer cells from various sample sources, helping customers understand the metabolic status of glycolytic pathways in real-time. Our experienced teams of scientists, researchers, and technicians provide fast turnaround, high-quality services at competitive prices for worldwide customers. Our customers have direct access to our staff and prompt feedback on their inquiries. If you are interested in our services, please contact us for more details.