CD BioGlyco provides a variety of different glycopeptides synthesis solutions, and can customize synthesis program according to customers' research needs. We have confidence to be your essential research assistant in the field of glycobiology.
Carbohydrates (glycans) are attached to amino acid side chains to produce glycoproteins. Glycoproteins play an important role in biological processes, such as cell adhesion, differentiation and proliferation, as well as many pathological processes of viral and bacterial infections and cancer metastasis. As a result, research interest in glycoproteins has been growing. Research in this field can help us understand glycobiology at the molecular level and provide novel ideas for the early diagnosis and treatment of human diseases.
The biosynthesis of oligosaccharides involves a series of enzymatic reactions that are not controlled by templates or transcription, so the process is easily affected by enzyme activity and substrate availability. Therefore, the glycans of each glycoprotein may have many different glycoforms. They are difficult to separate, almost impossible to obtain a homogeneous glycoform of glycoprotein from nature.
In recent years, new and effective methods for synthesizing these compounds have been developed, which allows researchers to explore glycopeptides at a deeper level. As a result, many vaccines are expected to be developed for HIV, cancer, or many other clinical diseases and novel antibiotics to overcome drug resistance.
Fig 1. Examples of N- and O-linked glycans found in mammalian glycopeptides. (Guo, Z.; Shao, N. 2005)
CD BioGlyco provides three strategies for glycopeptides synthesis using free glycans as key intermediates, or customized synthesis schemes based on customer's research needs.
CD BioGlyco has quite a wealth of experience in glycopeptide synthesis. Our efficient work and thoughtful service attitude have won us a lot of praise internationally.
Customers can contact our employees directly and we will respond promptly. If you are interested in our services, please contact us for more detailed information.