Arabino Galactan Analysis Service

Arabino Galactan Analysis Service

Excellence in Analysis: Your Arabino Galactan Solution

At CD BioGlyco, we are committed to advancing the Analysis of Pharmaceutical Excipients. We provide clients with comprehensive analytical services on arabino galactan as pharmaceutical excipients. Arabino galactan, also known as arabinogalactan, is a water-soluble polysaccharide extracted from the xylem of Larix gmelinii in the Pinaceae family. From a physical perspective, arabinogalactan is a white to light yellow powder that is easily soluble in water but insoluble in ethanol. This solubility property allows arabinogalactan to form mucus in water, and the mucus should be amber in color, which facilitates its application in pharmaceutical preparations. Below is our detailed analysis service of arabinogalactan from multiple aspects.

Analysis of arabino galactan. (CD BioGlyco)

  • Physical and chemical characterization

Arabino galactan is a white to light yellow powder. This color feature helps us observe and quality control it during the production process. At the same time, its easy solubility in water and insolubility in ethanol allows us to accurately measure its solubility and dissolution rate to evaluate its suitability as a pharmaceutical excipient.

In addition, we provide physicochemical characterization of arabino galactan, including molecular weight determination and structural analysis by nuclear magnetic resonance (NMR) and Fourier transform infrared spectroscopy (FTIR), and thermal analysis to ensure its suitability as an excipient.

  • Functional research

We provide functional analysis of arabino galactan, including solubility, viscosity, water absorption capacity, thickening effect, gelling properties, and emulsifying properties. We also provide compatibility analysis services with various drugs to ensure that the drug delivery system successfully produces minimal side effects.

  • Thickening effect analysis: Arabino galactan has a good thickening effect, which makes it an ideal suspending agent and adhesive in pharmaceutical preparations. We experimentally measure its thickening properties to evaluate its application in different pharmaceutical formulations.
  • Gelling property analysis: We conduct gel experiments to determine its gel-forming ability and stability to evaluate its potential application in pharmaceutical formulations.
  • Emulsifying performance analysis: Arabino galactan can be used as an emulsifier to make dairy products and milk fat substitutes, reducing the surface tension of water and oil and improving the stability of dairy products. We measure its emulsifying properties through emulsification experiments to evaluate its effect in improving the stability and solubility of pharmaceutical preparations.
  • Safety evaluation

As pharmaceutical excipients, safety evaluation is essential. We perform cytotoxicity assays, hemolysis tests, and immune response studies to evaluate the safety of arabino galactan as a pharmaceutical excipient in different settings.

  • Performance evaluation

We evaluate the performance of arabino galactan-based formulations, including their drug loading efficiency, stability, suitability for various routes of administration, and release kinetics of different drug classes.

  • Innovative applications

Our team investigates new potential applications of arabino galactans in pharmaceutical formulations. For example, we explore its role in nanoparticle production and the creation of novel drug delivery systems to ensure optimal efficiency and versatility.

  • Customized solutions

We provide customized arabino galactan analysis services based on the specific needs of our clients. For example, we adjust the dosage and ratio of arabino galactan to optimize the formula based on the needs of specific pharmaceutical preparations.

Publication Data

Technology: Review of the immunomodulatory effects of arabinogalactan and its role in fighting cold infections

Journal: Nutrition & metabolism

IF: 4.5

Published: 2016

Results: The authors aimed to investigate the immunomodulatory effects of larch arabinogalactan from North American larix species on resistance to common cold infections. In their research, they found that larch arabinogalactan enhanced natural killer cells and macrophages, along with boosting the secretion of pro-inflammatory cytokines in cell and animal models. Additionally, vaccination studies demonstrated improvements in serum antigen-specific IgG and IgE responses to Streptococcus pneumoniae and tetanus vaccinations, suggesting a B cell-dependent mechanism.

Fig.1 Possible ways in which larch arabinogalactan may affect the immune system.Fig.1 Proposed mechanisms of action of larch arabinogalactan on immune system. (Dion, et al., 2016)

Advantages of Us

  • We have a professional analysis team. Our analytical team consists of experienced professionals with a deep background in biology and chemistry who accurately interpret and analyze experimental data.
  • We focus on comprehensive services. When providing arabino galactan analytical services, we not only focus on its basic physical and chemical properties, but also conduct a comprehensive assessment of its functionality, safety, and interactions with other ingredients in pharmaceutical formulations.
  • We focus on client experience and feedback. We have always been client-centric and committed to providing a high-quality service experience.

Frequently Asked Questions

  • What is the main role of arabino galactan in pharmaceutical preparations?

Arabino galactan is often used as pharmaceutical excipients, suspending agents, and adhesives in pharmaceutical preparations. As a pharmaceutical excipient, it can enhance the stability and solubility of drugs and improve their bioavailability. As a suspending agent, it can evenly suspend drug particles in liquid and prevent precipitation and stratification of drug particles. As a binder, it can enhance the adhesion between drug particles and make the drug preparation stronger.

  • What are the key factors to consider when choosing arabino galactan as a pharmaceutical excipient?

When selecting arabino galactan as a pharmaceutical excipient, key factors to consider include its purity, molecular weight distribution, solubility, stability, and compatibility with other pharmaceutical ingredients. High-purity arabino galactan can reduce the impact of impurities on drug quality. Arabino galactan with a uniform molecular weight distribution provides better physical properties. Arabino galactan with good solubility can better mix with pharmaceutical ingredients. Arabino galactan's good compatibility with other pharmaceutical ingredients can avoid interactions between drug ingredients.

At CD BioGlyco, arabino galactan analysis service is one of our core services among the Pharmaceutical and Biological Analysis Services. We use advanced analytical technology and professional knowledge to conduct detailed physical properties, chemical structure, functionality, and safety evaluation of arabino galactan. We are committed to providing clients with accurate and reliable data support to assist in the development and production of pharmaceutical preparations. Please feel free to contact us if you are interested in our arabino galactan analysis service.

Reference

  1. Dion, C.; et al. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutrition & metabolism. 2016, 13(1): 28.
This service is for Research Use Only, not intended for any clinical use.

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