High-performance liquid chromatography with fluorescence detection (HPLC-FLD) combines ultra-high-performance liquid chromatography (HPLC) and fluorescence detection (FLD) to enable rapid separation as well as an accurate analysis of glycan from complex mixtures. With the increasing importance of sugars in life sciences, the need for high-throughput glycan screening is becoming more and more urgent. The traditional analysis methods for glycan have problems such as long time, complicated operation, and low detection sensitivity, which have been solved by the emergence of HPLC-FLD technology. The advantages of this technology are its strong separation ability, fast analysis speed, and high detection sensitivity, which can simultaneously detect a variety of glycan components and quantitatively analyze their contents. In recent years, the development of automated sample processing and data analysis methods has also supported high-throughput glycan screening. Therefore, the current development of high-throughput glycan screening using HPLC-FLD indicates that this technology has a promising application in the field of glycan analysis.
CD BioGlyco is a biotech company focused on the development of glycan analysis and screening platforms. We are committed to providing our clients with high-throughput glycan screening services to facilitate the development and production of glycan-related products. We offer the services following:
Fig.1 UHPLC-FLD-based glycan analysis. (CD BioGlyco, 2023)
CD BioGlyco is committed to providing high-quality high-throughput glycan screening services using UHPLC-FLD. Our professional team, advanced equipment, and strict quality control have equipped us to provide satisfactory products and services to our clients. If you are interested in our services, please contact us for more details.