Chitooligosaccharide Analysis Service

Biological Activities of Chitooligosaccharide (COS)

COS exhibits diverse physiological functions, including antioxidant, anti-inflammatory, metabolic regulation, antitumor, antibacterial activities, lowering blood cholesterol, lowering high blood pressure, preventing infection, controlling arthritis, improving calcium absorption, and enhancing anti-tumor properties.

Fig.1 A summary of the biological activities of COS. (Thomas, et al., 2023)

COS Analysis Service at CD BioGlyco

CD BioGlyco utilizes state-of-the-art analytical techniques and expertise to provide efficient Oligosaccharide Analysis Services for our clients, including chemical component analysis and structural analysis. Our attentive services are widely recognized. The specific services we offer include the following:

Nuclear magnetic resonance (NMR) spectroscopy
Determination of physicochemical properties

Physicochemical properties	Determination methods
Degree of deacetylation	Potentiometric method/FT-IR/acid-base titration
Degree of polymerization	MALDI-TOF MS; ¹H NMR
Degree of N-acetylation	MALDI-TOF MS; ¹H NMR; HPLC-a photodiode array (PDA)
Chemical structure	FT-IR/ESI-MS/UV
Viscosity	A falling-ball viscometer
Color tone intensity	Stereo microscope
Intrinsic viscosity molecular weight	An ubbelohde viscometer

Fig.2 The workflow of COS analysis. (CD BioGlyco)

Applications

COS has comprehensive applications in various fields including agriculture, pharmacy, clinical research, and environmental industries.
Chemical component analysis significantly promotes the research on relationships between COS structure and function.
Researchers utilize COS and their derivatives for various biomedical studies because of its greater solubility and low viscosity.

Advantages

MS has high sensitivity and is a natural choice for the analysis of oligosaccharides.
The main advantages of HPLC include excellent resolution, ease of use, and high recoveries.
Simple, fast, and perfect after-sale service.

At CD BioGlyco, the COS analysis service allows you to obtain a complete and detailed experimental analysis report. Our clients can directly contact our experts and provide timely feedback on any inquiries. If you are interested in our services, please feel free to contact us.

Reference:

Thomas, R.; et al. Green-chemical strategies for the production of tailor-made chitooligosaccharides with enhanced biological activities. Preprints. 2023, 28(18): 6591.

This service is for Research Use Only, not intended for any clinical use.