Metabolic reprogramming is a hallmark of cancer. Metabolites are not only intermediates in metabolic pathways, but also mediate epigenetic modifications, protein post-transcriptional modifications, and cell signaling. The intermediate metabolites of the tricarboxylic acid cycle can participate in various biological processes through various shuttle mechanisms. Glucose is decomposed into two molecules of pyruvate through the glycolytic pathway, and pyruvate is converted into acetyl CoA under the action of the pyruvate dehydrogenase complex. Acetyl-CoA then enters the TCA cycle. As a key part of glucose catabolism, the TCA cycle is strictly regulated. Therefore, the study of TCA cycle metabolites can provide new ideas for the study of glucose metabolic reprogramming in cancer. CD BioGlyco can provide quantitative analysis services of TCA cycle intermediate metabolites and functional analysis services of intermediate metabolites in cancer progression.
We provide the following TCA cycle metabolite analysis.
To explore the effects of acute administration of TCA cycle metabolic intermediate X in vivo and in vitro models.
CD BioGlyco can provide quantitative detection services for TCA cycle metabolic intermediates and their functional analysis services in cancer progression. Our experienced teams of scientists, researchers, and technicians provide fast turnaround, high-quality services at competitive prices for worldwide customers. Our customers have direct access to our staff and prompt feedback on their inquiries. If you are interested in our services, please contact us for more details.