Dextrate Analysis Service
Unmatched Dextrate Analysis to Aid Your Formulation Research
Pharmaceutical excipients not only maintain the stability, safety, or homogeneity of the preparation, but also promote drug dissolution, control drug release speed and release location, or serve as carriers to directionally transport drugs. With the development of pharmaceutical technology, pharmaceutical excipients have gradually attracted the attention of pharmaceutical researchers and have shown unique advantages in specific fields. CD BioGlyco assists clients in researching carbohydrate-related Pharmaceutical Excipients and provides analytical services such as physical property inspection, content determination, chemical identification, and determination of related substances. Our one-stop solution for Pharmaceutical and Biological Analysis also helps you analyze the performance of Pharmaceuticals and Biologicals.
Dextrate is a carbohydrate mixture obtained by enzymatic hydrolysis and purification of starch. It is available in anhydrous and hydrated forms and is used as pharmaceutical excipients or sweeteners. We provide worry-free dextrate property inspection, content determination, chemical performance testing, and other services.

- Physical property inspection
After receiving samples from clients, we check their appearance, color, and shape, and test their solubility in water, ethanol, propylene glycol, and dilute acid.
- Content determination
After checking the appearance and solubility, we test the glucose content of the sample. We use the glucose standard as a control and use the titration method to test the glucose content in the sample. Take the alkaline copper tartrate test solution and heat it to boiling. Then titrate it with the sample to be tested, rotate and shake continuously, add methylene blue solution near the endpoint, slowly titrate with the sample to be tested until the blue color disappears, and calculate the glucose content in the sample.
- Chemical performance testing
We refer to standard methods to help clients evaluate the pH, weight loss on drying, ignition residue, and heavy metals of samples.
Publication
Technology: Dextran excipients and human cell model
Journal: Processes
IF: 3.5
Published: 2022
Results: The authors used a specially designed human cell model to evaluate the effects of different concentrations of cellobiose, lactose, sucrose, trehalose, isoleucine, glycine, methionine, dextran, mannitol, and (2-hydroxypropyl)-β-cyclodextrin lyophilized formulation excipients on cell viability. The results showed that dextran was the only excipient that was well tolerated at concentrations up to 100 mg/mL, demonstrating high biocompatibility.
Fig.1 The graph represents the viability of lymphocytes after 48 h of treatment with the different excipients. (Susa, et al., 2022)
Applications
- Evaluate the consistency and purity of dextrate in pharmaceutical preparations to ensure drug quality.
- Use in the optimization of drug formulations to analyze the efficacy and stability of dextrate by testing its performance.
- Evaluate whether the dextrate in pharmaceutical preparations meets industry standards and regulatory requirements through a series of tests.
- Use to analyze dextran in cosmetics, food, agriculture, and other fields.
Advantages of Us
- We have developed a worry-free one-stop solution for pharmaceutical and biological analysis, not only providing analysis services for pharmaceutical and pharmaceutical excipients but also providing biological activity assessment services.
- Unlock dextrate's physical performance testing, content determination, and chemical property testing (such as pH). Identify potential contaminants and impurities to ensure safe and reliable drug formulations.
- Our experts provide data analysis and interpretation to assist your drug formulation development.
Frequently Asked Questions
- What are the precautions for the production and analysis of pharmaceutical excipients?
- The excipients used in pharmaceutical formulas comply with the quality supervision related to the production of pharmaceutical excipients.
- The excipients used in pharmaceutical formulas have stable chemical properties, are easy to store, and are not easily affected by temperature, humidity, and light.
- Pharmaceutical excipients meet the safety, stability, and effectiveness supervision of the preparation.
- What is the function of pharmaceutical excipients?
- Pharmaceutical excipients ensure the stability of the drug and prevent the degradation of active pharmaceutical ingredients.
- Pharmaceutical excipients improve the solubility of drugs and ensure that they are absorbed in the body.
- Certain excipients affect metabolic processes to improve drug absorption.
- Excipients control the location and time of drug release in the body to achieve targeted release.
- Excipients enhance the physical properties of drugs and optimize the drug's production process.
CD BioGlyco is based on standard analytical methods to help clients monitor every stage of dextrate formulation research. You can contact us at any time to obtain information about dextrate analysis services. If you have special testing needs, you can also contact us and we will provide you with customized solutions.
Reference
- Susa, F.; et al. Cytotoxicity and thermal characterization assessment of excipients for the development of innovative lyophilized formulations for oncological applications. Processes. 2022, 10(12): 2641.
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