Currently, more and more researchers are focusing on the development of glycobiology, which is not surprising considering that at least half of all proteins in organisms are equipped with glycans chains. These glycans are involved in many physiological interactions and directly or indirectly affect cellular functions. In glycobiology studies, understanding the precise glycan structures, the structural variability of glycans, the attachment sites of glycans to proteins, and the degree to which these sites are occupied is very necessary to study their functions.
In recent years, along with the deepening of genomics and proteomics research, various advanced biomass spectrometry and biochemistry techniques have been developed to provide scientists with reliable analytical tools, which is helpful to obtain more detailed information on glycoconjugates and their glycan chains structures. CD BioGlyco is dedicated to developing a one-stop service in the field of glycomics, from glycan release, separation, and purification, glycan derivatization to glycan characterization and quantification services, providing customers with scientific assistance in the field of glycomics.
Fig.1 General glycomic strategies. (Cummings, 2013).
CD BioGlyco has established a variety of chemical and enzymatic release strategies to release glycans from glycoproteins, providing the material basis for subsequent analysis of glycan structure.
CD BioGlyco provides glycan separation and purification services for our clients using advanced experimental instrumentation and strategies that combine multiple mass spectrometry techniques.
To improve the sensitivity and efficiency in glycan structures detection, CD BioGlyco provides a variety of glycans derivatization services to help customers obtain accurate structure information.
CD BioGlyco has a variety of efficient analytical strategies to provide glycan profiling, glycan sequencing, and glycan structure analysis to our customers.
CD BioGlyco has developed a variety of strategies for glycosylation quantitation to characterize site-specific glycan structures and glycosylation site occupancy.
CD BioGlyco has high-tech analysis equipment to provide one-stop service in terms of glycomics for clients. We have supplied professional technical services to thousands of enterprise customers and established long-term cooperative relations. We have accumulated lots of successful experiences in the field of glycomics services. Please feel free to contact us to obtain further information.