Anticoagulant Heparin Solution Analysis Service

Anticoagulant Heparin Solution Analysis Service

Your Trusted Partner for Accurate Anticoagulant Heparin Solution Analysis

Anticoagulant heparin solution is a medicated solution that contains heparin, an active ingredient that prevents the formation of blood clots by blocking a key step in the blood clotting process. In addition to its anticoagulant effects, heparin has other important physiological functions. For example, it plays an important role in the regulation of cell proliferation, immune response, and control of inflammatory response in vivo. Therefore, the analysis of anticoagulant heparin solution holds significant importance in the field. CD BioGlyco provides a full range of anticoagulant heparin solution analysis services to clients with our advanced technology and extensive experience in Pharmaceutical Analysis.

  • We utilize the binding reaction of human factor Xa to a specific substrate to help you determine the amount of anticoagulant heparin in your sample by observing the time it takes for the substrate to convert to the product.
  • High-performance liquid chromatography (HPLC) is employed to effectively separate the components in the samples based on their distinct affinities for the stationary phase. Subsequently, we determine the content of these components by analyzing their elution times and peak sizes after passing through the column.
  • By using surface-enhanced Raman spectroscopy (SERS), we perform the detection of components in anticoagulant heparin. It is an emerging and highly sensitive analytical technique that combines the effects of surface enhancement and Raman scattering to rapidly and accurately detect a wide range of components in anticoagulant heparin solutions at low concentrations.
  • CD BioGlyco utilizes differences in the charge-to-mass ratios of anticoagulant heparin solutions to differentiate them from the other components and test them quantitatively. By taking advantage of these distinct properties, we effectively distinguish anticoagulant heparin solutions from other substances present by the mass spectrometry. This quantitative testing allows you to accurately measure and analyze the specific characteristics of each solution, providing valuable insights into their composition and potential applications for you.

Fig.1 Technologies for anticoagulant heparin solution analysis service. (CD BioGlyco)Fig.1 Technologies for anticoagulant heparin solution analysis service. (CD BioGlyco)

Publication Data

Technology: Surface plasmon resonance

Journal: Analytical Biochemistry

IF: 3.191

Published: 2017

Results: This article describes a new method for measuring the anticoagulant activity of heparin using the surface plasmon resonance (SPR) technique. The method assesses the anticoagulant activity of heparin by measuring the interaction between heparin and antithrombin III (AT). Specifically, the researchers immobilized heparin on the SPR chip and observed its binding to heparin by injecting an antithrombin III solution. By monitoring the degree of binding between heparin and AT, the anticoagulant activity of heparin can be accurately measured. This method is rapid, sensitive, and accurate, and can provide a new option for the measurement of heparin anticoagulant activity.

Fig.2 Diagram of SPR solution competition experiment for anticoagulant activity measurement of heparin samples. (Zhao, et al., 2017)Fig.2 Diagram of SPR solution competition experiment for anticoagulant activity measurement of heparin samples. (Zhao, et al., 2017)


  • Our analytical technology accurately measures a variety of parameters in blood samples, including coagulation factor activity and concentration.
  • Our method exhibits high sensitivity and is capable of precisely detecting and quantifying subtle variations in samples.
  • Through regular reporting and updates on project progress, we ensure that our clients are fully informed of the status of their projects and are involved in the decision-making process.

In brief, CD BioGlyco is a dependable ally for individuals in need of trustworthy anticoagulant heparin analysis services. We are leading the way in this domain and are fully prepared to make substantial contributions toward enhancing healthcare through efficient analytical solutions. For further details, please don't hesitate to contact us.


  1. Zhao, J.; et al. Novel method for measurement of anticoagulant activity using SPR. Analytical biochemistry. 2017, 526: 39-42.
  2. Qu, G.; et al. A "turn-off" SERS assay of heparin with high selectivity based on heparin-peptide complex and Raman labeled gold nanoparticles. Biosensors and Bioelectronics. 2014, 60: 124-129.
This service is for Research Use Only, not intended for any clinical use.

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