Glucosamine Indometacin Enteric Capsule Analysis Service

Glucosamine Indometacin Enteric Capsule Analysis Service

Promote Your Project Development with Glucosamine Indometacin Enteric Capsule Analysis

Glucosamine indometacin enteric capsule is a compound preparation, the main ingredients are indomethacin and glucosamine hydrochloride. Indomethacin is a non-steroidal anti-inflammatory drug with antipyretic, analgesic, and anti-inflammatory effects. Glucosamine hydrochloride promotes the biosynthesis of hyaluronic acid and proteoglycan and inhibits macrophage production of superoxide free radicals and enzymes with destructive effects on articular cartilage. Characterization and quantification of the major components of glucosamine indometacin enteric capsule is an important part of Pharmaceutical and Biological testing. CD BioGlyco has developed an efficient and convenient analysis for the simultaneous determination of indomethacin and glucosamine hydrochloride.

  • Quantitative analysis
    • CD BioGlyco determines the content of indomethacin and glucosamine hydrochloride by various analytical methods such as volumetric analysis, ultraviolet (UV)-visible spectrophotometry, and high-performance liquid chromatography (HPLC). We provide HPLC-charged aerosol detectors (HPLC-CAD) and HPLC-UV analyses.
    • Our professional staff examines and optimizes the test solution, mobile phase, and detector to ensure the best separation and detection. For example, we use gradient elution to ensure that the two main components peak in a reasonable time, and to meet the requirements of the main peak and auxiliary peaks to achieve baseline separation.
  • Crystal type test
    • Indomethacin has a polymorphism phenomenon and is prone to form solvent compounds. Determination of the crystalline form of the active pharmaceutical ingredient (API) in the formulation is a guarantee for safe drug use. We use powder X-ray diffraction (PXRD) to quantitatively analyze the content of indomethacin crystalline form γ in glucosamine indometacin enteric capsule. Moreover, we provide different batches of crystal-type comparison services.
  • Dissolution rate analysis
    • Disdissolution of Pharmaceuticals in the human body is a key factor in determining drug efficacy. We provide glucosamine indometacin enteric capsules for in vitro dissolution analysis. The dissolution of indomethacin in glucosamine indometacin enteric capsules is determined by HPLC after sampling at the specified time.

Fig.1 Schematic diagram of glucosamine indometacin enteric capsule analysis tools. (CD BioGlyco) Fig.1 Schematic diagram of glucosamine indometacin enteric capsule analysis tools. (CD BioGlyco)

Applications of Glucosamine Indometacin Enteric Capsule Analysis

  • Glucosamine indometacin enteric capsule analysis is an effective tool to detect the difference in the preparation process.
  • Glucosamine indometacin enteric capsule analysis is a scientific means for evaluating the intrinsic quality of oral preparations.
  • Glucosamine indometacin enteric capsule analysis promotes the development of dissolution behavior studies of insoluble heterolytic preparations.

Advantages of Us

  • The HPLC-CAD analysis service we offer has the advantages of high sensitivity, reproducibility, and stability, and can be used for quantitative or semi-quantitative analysis.
  • We use fine scanning, which is suitable for the quantitative detection of large batch samples.
  • Our company quickly delivers the analysis report and the raw data.

CD BioGlyco has many years of extensive experience in pharmaceutical and biological analysis. If you are interested in glucosamine indometacin enteric capsule analysis, rest assured that we have a perfect technical team, and the most advanced approaches to meet all your requirements. Please feel free to contact us.

References

  1. Park, S.H.; et al. Nonsteroidal anti-inflammatory drugs (NSAID) sparing effects of glucosamine hydrochloride through N-glycosylation inhibition; strategy to rescue stomach from NSAID damage. J Physiol Pharmacol. 2013, 64(2): 157-65.
  2. Cox, P.J.; Manson, P.L. γ-Indomethacin at 120 K. Acta Crystallographica Section E: Structure Reports Online. 2003, 59(7): o986-o988.
This service is for Research Use Only, not intended for any clinical use.

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