More research focuses on the structure and function of glycolipids, and the important prerequisite for studying glycolipids is to obtain high-purity glycolipid samples. Our scientists are experienced in glycolipid separation and profiling, and we have the confidence to be your essential research assistant in the field of glycobiology.
Carbohydrates mainly exist in the form of sugar complexes in organisms, including glycoproteins, proteoglycans and glycolipids. The basic structure of glycolipids is formed by connecting the hemiacetal hydroxyl groups of sugars with lipids through glycosidic bonds. It is a type of amphiphilic molecule that exists widely in organisms.
Glycolipids are often used as cell surface markers. It is also an important component of cell surface antigens. After some normal cells become cancerous, the surface glycolipids composition changes significantly, some isolated cancer cell characteristic antigens have also been shown to be glycolipids. The glycolipids on the cell surface are also receptors for many extracellular physiologically active substances, participating in cell recognition and information transmission. Over the years, a variety of glycolipid profiling strategies have been developed to directly promote the development of glycobiology, and these need to be based on advanced glycolipid separation technology.
Fig 1. Glycolipids with sterol, ceramide or diacylglycerol as hydrophobic backbone (Cortés-Sánchez, A. J.; et al.)
At CD BioGlyco, we use the following methods to perform glycolipid separation.
CD BioGlyco provides a variety of advanced technology platforms for customers to solve various problems encountered in the separation and purification of glycolipids, and finally provide high-purity glycolipids for subsequent experimental use.
Customers can contact our employees directly and we will respond promptly. If you are interested in our services, please contact us for more detailed information.