Arabinan, also known as gum arabic, possesses a backbone of α(1-5)-linked L-arabinofructan units and is a neutral polysaccharide with only L-arabinose as a constituent (mono) sugar. Arabinan is named for its earliest isolation from gum arabic. Compared with other common sugars, arabinan has a lower calorie content, which allows it to satisfy taste needs while controlling energy intake. Arabinan also has the property of dietary fiber, which promotes intestinal peristalsis, helping to relieve constipation symptoms and improve digestive health. In addition, arabinan can inhibit the rise in blood sugar caused by the intake of sucrose and therefore can inhibit obesity and prevent and treat diseases related to high blood sugar. On the other hand, arabinan has the effect of altering the composition of skeletal muscle fibers, affecting the growth of abdominal adipose tissue by governing glycolysis to sugar oxidation.
CD BioGlyco has accumulated extensive experience in the Analytical Study of Polysaccharides and therefore we offer comprehensive arabinan analysis services.
Fig.1 Analytical procedure of arabinan. (CD BioGlyco)
Paper Title: Structural elucidation of an immunological arabinan from the rhizomes of Ligusticum chuanxiong, a traditional Chinese medicine
Technology: NMR analysis
Journal: International Journal of Biological Macromolecules
Results: 1H, 13C, heteronuclear singular quantum correlation (HSQC), and heteronuclear multiple bond correlation (HMBC) NMR of an immunological arabinan (LCP70-2A) were shown in Fig.2. For the furanose residues forming glycosidic linkages, the chemical shifts of anomeric were in the range of 105-110 ppm when in an α configuration according to the literature. Thus, both the sugar residues of LCP70-2A were determined to be in α configuration. The linkage sites and sequences of the sugar residues in LCP70-2A were further confirmed by analyzing the correlation peaks in the HMBC spectrum.
Fig.2 1H, 13C, HSQC, and HMBC NMR spectra of LCP70-2A. (Zhang, et al., 2021)
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