Plant polysaccharides play an increasingly important role in pathology and pharmacology, CD BioGlyco provides advanced and alternative polysaccharide separation methods to meet customers' needs, and we have confidence to be your essential research assistant in the field of glycobiology.
Plant polysaccharides refer to complex and large carbohydrates synthesized by the condensation and dehydration of multiple monosaccharide molecules in plants. Its structure usually contains linear and branched chains, with a molecular weight distribution in the range of tens of thousands to millions. More studies have been conducted on plant polysaccharides in recent years, and polysaccharides have been extracted from hundreds of plants.
These plant polysaccharides have essential and unique biological activities, including signal recognition, cell connection, immune system regulation, and blood coagulation. At present, numerous studies have reported that they also have a wide range of pharmacological activities, such as anti-tumor, anti-virus, cardiovascular protection, etc. Polysaccharides with multiple functional chemical groups (hydroxyl, amino and carboxylic acid group) can be further modified for the use in biomedical field, such as vaccine adjuvants, drug carriers, tissue engineering, etc. However, due to the complexity of its functions and structures, the understanding of plant polysaccharides is still very limited, and the important prerequisite for the study of plant polysaccharides is high-quality purification and separation.
Fig 1. Literature analysis of natural polysaccharide extractions and polysaccharide synthesis with the statistical data coming from the web of science (Ren, Y.; et al. 2019)
The main principle of plant polysaccharide extraction is to break the cell wall from outside to inside under mild conditions, thereby avoiding polysaccharide denaturation. Polysaccharides extracted from natural products contain many impurities, such as inorganic salts, proteins, lignin, etc. Therefore, certain measures need to be taken to separate crude polysaccharides and the mixture of different polysaccharides needs to be purified into a single polysaccharide component with the same degree of polymerization and spatial conformation.
We use the following methods for plant polysaccharides separation.
Fig 2. Extraction and purification methods of plant polysaccharides in CD BioGlyco - CD BioGlyco
CD BioGlyco provides a variety of methods to meet the research needs of customers, and customize different experimental programs according to the characteristics of different samples. We use professionalism and efficiency to complete customer's orders and save time and funds for customers while obtaining credible results.
Customers can contact our employees directly and we will respond promptly. If you are interested in our services, please contact us for more detailed information.