Disaccharide-based Biodegradable Material Development

Disaccharide-based Biodegradable Material Development

Thoughtful Disaccharide-based Material Development Service to Meet Client Needs

CD BioGlyco develops a wide range of Carbohydrate-based Biodegradable Materials for biomedical, industrial, and food applications based on advanced technology and equipment. Disaccharides have good biocompatibility, degradability, and natural bioactivity and are widely used in the development of bio-based materials. We provide a high-quality development service for disaccharide-based biodegradable materials based on the principle of non-toxicity to humans and the environment during use and disposal.

We develop biodegradable materials ranging from polyurethane foams for industrial applications to hydrogels for biomedical applications. There are two main strategies for our development. One is the direct polymerization of disaccharides as raw materials. The other is to incorporate disaccharides into synthetic polymers. We are proficient in technologies related to the development of disaccharide-based biodegradable materials, such as injection, direct blending, extrusion, foaming, and solvent casting. The process of developing disaccharide-based biodegradable materials is as follows:

  • The design and preparation of the material: We are equipped with a team of specialized scientists and engineers to develop one-stop solutions from design, and preparation to analysis. According to the specific application requirements, during the preparation process, we chemically modify the disaccharide by introducing different functional groups to influence the structure of the final material.
  • Analysis of materials: We characterize the developed disaccharide-based materials by Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR), electron microscopy and exclusion chromatography, physical and mechanical tests, biodegradability determination, and biodegradability.

Flowchart of disaccharide-based biodegradable material development.Fig.1 Flowchart of disaccharide-based biodegradable material development. (CD BioGlyco)

We have further subdivided this service into two parts to better support and serve our clients in the development of biodegradable materials.

Sucrose-based Biodegradable Material Development

Sucrose is an attractive raw material due to its hydrophilic nature and large number of hydroxyl functional groups. CD BioGlyco is skilled in technologies related to biodegradable materials based on sucrose, including compression molding, reaction extrusion, etc.

Lactose-based Biodegradable Material Development

Lactose is rich in hydroxyl functional groups and is easily functionalized, making it attractive as a raw material for the preparation of hydrophilic materials. CD BioGlyco develops biodegradable materials such as lactose-based films and hydrogels for food packaging and drug delivery.

Publication Data

Technology: Direct blending

Journal: Journal of Applied Polymer Science

IF: 1.866

Published: 2015

Results: In this study, new functional elastic polyurethane foams (PUF) were synthesized from isocyanate precursors based on disaccharides (sucrose, lactose, maltose). The material retains the inherent properties of conventional foams and is degradable under both biotic and abiotic environmental factors. This study provides an effective strategy for the development of disaccharide-based biodegradable materials.

FTIR-spectra of synthesized PUF: (1) PUF-M, (2) Lactose, (3) PUF-4.Fig.2 FTIR-spectra of synthesized PUF: (1) PUF-M, (2) Lactose, (3) PUF-4. (Savelyev, et al., 2015)

Frequently Asked Questions

  • Why do researchers choose carbohydrates for biodegradable materials?
  • Compared to other synthetic polymers, carbohydrate-based biomaterials are biocompatible, biodegradable, and non-immunogenic, making them particularly suitable for in vivo therapeutic research, food packaging, wastewater treatment, and other applications.

    • What are the factors that need to be taken into account for the development of biomedical degradable materials?

    Biomedical degradable materials generally refer broadly to all materials that are degradable and absorbable in living organisms, i.e., materials that can be progressively broken down or destroyed when implanted in the body and over some time. The material will break down or degrade into non-toxic small molecules and be eliminated from the body without the need for a second surgery after its mission is accomplished. The constituent units or degradation products of most biomedical degradable materials are small molecules that exist in the organism itself, which have better biocompatibility and biosafety than non-degradable materials. The basic requirements are good biocompatibility, non-toxicity of the polymer itself and the degradation products; the required degradation rate, appropriate physical and mechanical properties, and moldability.

    Advantages of Us

    • We provide reliable and responsive support with our technical expertise and superior biodegradable material preparation capabilities.
    • We add disaccharides to the macromolecular structure to increase the degradability of polymers, which is one of the most effective ways to overcome environmental pollution from plastic waste.
    • The materials we develop are analyzed very thoroughly and meticulously to ensure their performance.

    CD BioGlyco has made good progress in the development of biodegradable materials based on carbohydrates. We focus on where our clients need us and give good solutions. Please feel free to contact us for more details about disaccharide-based biodegradable material development.


    1. Savelyev, Y.; et al. Degradable polyurethane foams based on disaccharides. Journal of Applied Polymer Science. 2015, 132(25).
    2. From Wikipedia:
    This service is for Research Use Only, not intended for any clinical use.

    About Us

    CD BioGlyco is a world-class biotechnology company with offices in many countries. Our products and services provide a viable option to what is otherwise available.

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