Mannose is a monosaccharide that is widely used in food, medical, and other industries. Based on our comprehensive Carbohydrate Metabolism Analysis solutions, CD BioGlyco provides mannose analytical services in various samples for our clients.
Mannose is a natural bioactive monosaccharide found in plants, animals, and microorganisms. It is the C-2 epimer of glucose and usually exists in the pyranose and furanose forms. In nature, mannose exists in the form of homopolymers or heteropolymers in most cases, such as yeast mannan. However, there is a small amount of free mannose in oranges, apples, and other fruits and mammalian plasma. At present, mannose has been widely used in the food, pharmaceutical, and chemical industries. For example, mannose is popular as a ready-to-use dietary supplement.
Fig.1 Mannose structure. (Wikipedia)
In plants, free mannose originates mainly from the degradation of hemicellulose and cellulose, which are then thoroughly metabolized in plant tissues. In microorganisms, mannose can participate in the ketose metabolism of various microorganisms. After being transferred by the cell membrane, mannose can be converted to fructose by mannose isomerase. Mannose is an essential glyconutrient for human health and can be obtained from dietary supplements or specific glycoproteins and glycolipids. Mannose in the human body is mainly absorbed and metabolized by the intestinal tract. Studies have shown that mannose is beneficial for diabetes, intestinal diseases, immune diseases, and more.
Fig.2 Mannose metabolic pathway. (Hu, 2016)
As a potential and valuable ingredient, mannose is widely used in food, medicine, and other industries. Therefore, the development of qualitative and quantitative methods based on mannose has also become increasingly important. CD BioGlyco provides mannose analytical services in various samples for our clients. Our analytical methods include:
We can determine the mannose content of the samples by HPLC with a refractive index detector. This method is suitable for the determination of mannose in mixed solutions.
This method is applied to the analysis of mannose in plant, food, and biological samples.
This method is suitable for the analysis of mannose in polysaccharide or polymer samples.
CD BioGlyco has been committed to carbohydrate metabolism research for many years and accumulated rich experience. We provide accurate, reproducible, and low-cost mannose analysis services for our clients worldwide. If you are interested in our services, please feel free to contact us, we are looking forward to being your research assistant in the field of carbohydrate metabolism analysis.