Traditional methods for glycan analysis require a lot of manual operations and analysis, which are inefficient and error-prone. High-throughput automated micro-permethylation technology allows automatic micro-permethylation operations after certain sample pretreatment. The results are analyzed and measured by high-throughput technical means, substantially improving the efficiency and accuracy of the analysis. In this process, the glycan sample first needs to be pretreated to make it more susceptible to the action of micro-permethylation reagents. Next, the micro-permethylation reaction is performed automatically using high-throughput automated equipment to methylate the glycan molecules therein. Finally, the samples are analyzed and detected by mass spectrometry to derive information about the glycan structure. This technique is an important advance in glycan structure analysis as it effectively reduces the time and errors of manual manipulation. By using this technique, researchers can rapidly and accurately analyze a large number of glycan structures and decipher their functions and roles.
Fig.1 Schematic diagram of the permethylation procedure using an automated 96-well pipet. (Shajahan, et al., 2018)
CD BioGlyco is committed to providing comprehensive solutions to our clients through advanced technologies and high-quality services. We provide services related to analyzing glycan structures by high-throughput automated micro-permethylation. Our services enable more precise analysis and research on different glycan structures. The specific services we offer include but are not limited to the listed below:
Fig.2 The process of glycan structure analysis by high-throughput automated micro-permethylation. (CD BioGlyco, 2023)
CD BioGlyco offers the service of analyzing glycan structures by high-throughput automated micro-permethylation technology. Our service helps our clients analyze complex glycan structures quickly and accurately to advance their relevant research. If you are interested in our services, please feel free to contact us for further information.