Ferrous GIuconate Analysis Service

Ferrous GIuconate Analysis Service

Reliable Analysis Service for Ferrous GIuconate in Various Forms

Ferrous gluconate is ferrous gluconate salt dihydrate and is a common iron fortifier. Ferrous gluconate is soluble in water, easily absorbed, and has low gastrointestinal irritation and high bioavailability. CD BioGlyco has experienced operators to provide clients with comprehensive analytical services for ferrous gluconate. Meanwhile, we provide analysis for ferrous gluconate tablets, ferrous gluconate capsules, and ferrous gluconate syrup. We are committed to being your first choice for the Pharmaceutical Analysis program.

Fig.1 The structural formula of ferrous gluconate. (CD BioGlyco)Fig.1 The structural formula of ferrous gluconate. (CD BioGlyco)

Ferrous GIuconate Analysis Service at CD BioGlyco

  • Identification and basic test
    Our lab provides rapid identification by adding phenylhydrazine and potassium ferricyanide test solution and observing the precipitation and crystallization phenomena. Moreover, we provide various test services including acidity, clarity, dry lost weight, and heavy metals test.
  • Compound determination
    We provide the following determination services for a variety of compounds:
    • Chloride
    • Oxalate
    • Calcium salt
    • Sulfate
    • Sucrose
    • Ferric salt
    • Barium salt
    • Reducing sugar
    • Arsenic salt
  • Content determination
    We use spectrophotometry or high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) for the determination of ferrous gluconate. Not only the content of ferrous gluconate can be determined but also its derivatives can be identified and quantified. Our research team evaluates the linearity, the matrix effect, the limit of detection (LOD), the limit of quantification (LOQ), the accuracy, and the precision, and ensures the optimal validity of the liquid phase system.

Fig.2 Schematic diagram of ferrous gluconate analysis service. (CD BioGlyco) Fig.2 Schematic diagram of ferrous gluconate analysis service. (CD BioGlyco)

Publication Data

Technology: Ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)

Journal: Applied Biological Chemistry

Published: 2023

IF: 3.2

Results: In this study, a new method for the quantitative analysis of ferrous gluconate was developed using UPLC-MS/MS. The validity of the method was verified by the researchers through various evaluation combinations. In addition, researchers used the UPLC-MS/MS system combined with electrospray ionization (ESI) to identify and quantify ferrous gluconate. The results showed that LOQ and LOD of ferrous gluconate were 3.5 and 1.1 mg/kg, respectively.

Fig.3 Chromatograms of ferrous gluconate by UPLC-MS. (Park, et al., 2023) Fig.3 Chromatograms of ferrous gluconate by UPLC-MS. (Park, et al., 2023)

Advantages of Us

  • The HPLC-MS/MS we provide is used not only for ferrous gluconate but also for Calcium Gluconate.
  • In conjunction with the feature of ferrous gluconate, our researchers evaluate the type and addition of ion-pairing reagents as well as the range of pH to ensure that ferrous gluconate, which does not have a characteristic absorption peak, has a much-improved retention time and peak shape on the stationary phase.
  • Our analysts immediately deliver the data reports to clients.

CD BioGlyco is recognized for providing high-quality Pharmaceutical and Biological Analysis services to clients in many countries. Our staff always serve you with a philosophy of enthusiasm and professionalism. Please feel free to contact us, and we will reply to you as soon as possible.


  1. Park, Y.J.; et al. Simultaneous quantification of ferrous gluconate and calcium gluconate in foods using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Applied Biological Chemistry. 2023, 66(1): 31.
This service is for Research Use Only, not intended for any clinical use.

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