Fructose Analysis Service

Fructose Analysis Service

Fructose is a monosaccharide that is widely used in food, medical, and other industries. Based on our comprehensive Carbohydrate Metabolism Analysis solutions, CD BioGlyco provides customers with fructose analytical services in biological samples.

What Is Fructose?

Fructose is a simple ketose found in many fruits and vegetables, such as apples, watermelons, and oranges. Fructose was first isolated from sucrose in 1847 by the French chemist Augustin-Pierre Dubrunfaut. Now, fructose has been widely used in the food, pharmaceutical, and chemical industries. In food, fructose is used as the main sugar-containing additive in beverages and desserts. To make it more palatable, fructose is added to the drug as an excipient. In the chemical industry, fructose is the starting material for the formation of bio-based. In addition, fructose is the main component of sucrose, fructan, and inulin.

Mannose structure.Fig.1 Fructose structure. (Wikipedia)

Fructose Metabolism

Fructose, glucose, and galactose are three dietary monosaccharides that can be absorbed directly into the bloodstream by the body. The main site of fructose metabolism is the liver, where fructose is phosphorylated to form fructose-1-phosphate. Under the action of liver aldolase, fructose-1-phosphate is cleaved to form glyceraldehyde and dihydroxyacetone phosphate (DHAP). DHAP is an intermediate metabolite of glycolysis and gluconeogenesis. Glyceraldehyde is phosphorylated to form glyceraldehyde-3-phosphate, another intermediate in glycolysis. Studies have shown that fructose has potential adverse effects on lipid metabolism, body weight, and more. Long-term intake of high levels of dietary fructose increases the risk of coronary heart disease.

Mannose metabolic pathway.Fig.2 Fructose metabolic pathway. (Tappy, 2010)

Our Services

Fructose is both a monosaccharide and a major component of the disaccharide sucrose. Based on the wide application of fructose in food, medicine, and other industries, it is important to develop methods suitable for the qualitative and quantitative analysis of fructose. CD BioGlyco provides customers with fructose analysis services in biological samples. Our analytical methods include but are not limited:

  • High-performance liquid chromatography (HPLC): We can determine the fructose content in the samples by HPLC with a refractive index detector.
  • Capillary electrophoresis (CE): This method is mainly used for fructose analysis in samples containing various carbohydrates.

In addition, we can also provide customized solutions based on your specific needs.

CD BioGlyco has been committed to carbohydrate metabolism research for many years and accumulated rich experience. We provide accurate and reproducible fructose analysis services for our global customers. If you are interested in our services, please feel free to contact us, we are looking forward to being your research assistant in the field of carbohydrate metabolism analysis.

References:

  1. Tappy, L.; Lê, K.A. Metabolic effects of fructose and the worldwide increase in obesity. Physiological reviews. 2010.
  2. Barclay, T.; et al. The chemistry and sources of fructose and their effect on its utility and health implications. Journal of Excipients and Food Chemicals. 2012, 3(2): 67-82.
This service is for Research Use Only, not intended for any clinical use.

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