CD BioGlyco is a world-leading company that can provide the best solutions for global customers in the field of microarrays. We have successfully developed many Glycobiology Arrays and corresponding testing services to accelerate the high-throughput detection of glycosylated proteins in biological samples. Lectin array is one kind of our glycobiology arrays. We guarantee to provide first-class array screening service to customers all over the world.

Introduction of Lectin

Lectins are a variety of proteins that specifically bind to carbohydrate residues of glycoproteins and glycolipids. More than 300 lectins have been found in various species from viruses, bacteria to plants and animals. These proteins play a role in identifying molecules in cell-molecule and cell-cell interactions. This is related to many basic biological processes, including cell proliferation, apoptosis, migration, white blood cell homing and transportation, and microbial infection. The wide range of applications of lectins includes the application in blood typing, as histochemical and cytochemical reagents, to detect glycoconjugates on tissue sections, cells and subcellular organelles, and to study the glycosylation of proteins in intracellular pathways. Immobilized lectins are usually used to separate and purify glycoproteins, glycopeptides and oligosaccharides. Lectin microarrays have been developed for rapid and sensitive analysis of glycans in a high-throughput manner. This is a new technology that uses a set of lectins immobilized on a well-defined substrate for high-throughput analysis of glycans and glycoproteins.

Applications of Lectin Array

As a high-throughput platform for glycan analysis, lectin microarrays have become a promising technology in the field of glycomics and glycoproteomics. Lectins displayed in the form of microarrays can perform rapid, sensitive and high-throughput analysis of glycan structures with subtle differences. Lectin microarrays are widely used, such as microbial typing and glycan identification in recombinant protein production. Biotechnology production of recombinant human protein drugs can use lectin array assays to process multiple sample screening tools in parallel, making it possible to monitor the glycosylation distribution of protein drugs at all stages of clone selection and optimization, process development and production. This technology makes use of the key role played by lectins in many biological pathways and helps research to clarify the important dynamic functions of carbohydrates in life activities. Lectin microarrays may also have great potential in the research of disease biomarkers. Lectin microarrays may become a promising tool for high-throughput analysis of tiny clinical samples to identify glycoprotein biomarkers for cancer detection.

• Glycoform characterization
• Concentration determination, low-concentration glycoprotein signal amplification
• Screening of disease-related carbohydrate/glycoprotein biomarkers
• Characterization of the glycan structure of the masked pathogen.

Features

• A variety of specifications, a variety of options;
• Wide range of application scenarios, suitable for a variety of experimental purposes.

CD BioGlyco provides high-quality array screening services for the rapid detection of glycosylated proteins. We provide commercialized arrays and customized array services for glycomics analysis according to your research goals. With a large team of scientists and a well-equipped array production platform and testing experiment platform, we offer a comprehensive combination of laboratories and manufacturing services. We have comprehensive capabilities and are committed to working with customers all over the world to meet your specific requirements. Please contact us for more details.