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High-Throughput Screening of Fucose

Significance for High-Throughput Screening (HTS) of Fucose

Fucose is an important source of energy in animals, and it has a role in organisms to protect biological macromolecules such as membrane proteins, cell membranes, and biofilms. It is also considered a natural immunomodulator and has an important role in the treatment of resistance to pathogens, inflammation, and tumors, and is widely used in pharmaceuticals, food, cosmetics, and biotechnology. Fucose has been studied for its potential efficacy in anti-tumor, anti-inflammatory, and antibacterial applications. HTS of fucose samples evaluates the activities and effects and provides potential candidates for drug development. Meanwhile, fucose, as a natural algal polysaccharide, has a variety of healthcare functions. HTS of fucose can rapidly characterize its content and structure, and assess its health benefits such as antioxidant, immunomodulatory, antithrombotic, and lipid-lowering effects. This helps develop high-quality functional foods and health supplements to meet consumer demand for healthy foods.

Fig.1 Structure of L-fucose. (Wikipedia)

HTS of Fucoseat CD BioGlyco

By studying the biochemical properties and biological activities of fucose, the structure and function of polysaccharides can be better understood, providing a basis for the development of novel polysaccharide drugs and biologics. CD BioGlyco provides comprehensive and specialized high-throughput glycan screening services including customized high-throughput fucose screening services for our clients. The services we provide include but are not limited to:

HTS of fucose by Glycan Microarrays

Glycan microarrays allow rapid and high-throughput determination of glycol-receptor interactions to assess the affinity and specificity of the selected algal glycans. This technology is also available in very small quantities, thus significantly reducing sample usage and reagent consumption.

HTS of fucose by Capillary Electrophoresis-Mass Spectrometry (CE-MS)

CE-MS can be used to isolate fucose from different samples and to rapidly detect and analyze them by Mass Spectrometry. This technique causes no permanent damage to the sample and allows for subsequent research and analysis of the product.

Fig.2 Technologies for HTS of fucose. (CD BioGlyco)

Applications

Glycan drug development and evaluation
Studies on the interaction of glycans with other biomolecules
Studies on the anti-tumor and anti-inflammatory activities of fucose

Advantages of Us

Diversity and high throughput
Real-time monitoring
Low reagent and time consumption

CD BioGlyco provides customized high-throughput fucose screening services with specialized knowledge and extensive experience. We utilize an automated process that allows us to handle large volumes of samples at the same time, dramatically shortening test cycles and increasing efficiency. We hope to be your effective and trustworthy assistant in glycobiology research. If you are interested in our services, please contact us for more details.

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