Interplay Between Glucose Metabolism Reprogramming and Tumorigenesis & Progression

Home
Platforms
Multi-omics Platform for Cancer Glucose Metabolism (MOPCGM)
Interplay Between Glucose Metabolism Reprogramming and Tumorigenesis & Progression

Platforms

Featured Platforms

Featured Services

Online Inquiry

Interplay Between Glucose Metabolism Reprogramming and Tumorigenesis & Progression

A large number of studies have found that abnormal glucose metabolism exists before the occurrence of many cancers, and abnormal glucose metabolism, as a key link in energy reprogramming, is closely related to the occurrence and development of cancer. The process of tumorigenesis is the process by which cancer cells acquire the ten hallmarks of tumors, and the process of tumor progression is the process by which cancer cells maintain the ten hallmarks of tumors. Therefore, studying the reprogramming of glucose metabolism is crucial for a comprehensive understanding of the mechanism of tumorigenesis and development, and can also bring new hope for the clinical treatment and diagnosis of cancer. CD BioGlyco can provide analysis services for the relationship between glucose metabolism reprogramming and cancer characteristics based on the MOPCGM platform.

What We Do

Interplay Between Glucose Metabolism Reprogramming and Proliferative Signaling

Glucose is involved in the continued proliferation of cancer cells as the main energy source. On the one hand, proliferative signals can regulate the reprogramming of glucose metabolism, on the other hand, glucose metabolism disorders also have a regulatory effect on cancer cell proliferation. We are able to help customers solve difficult problems in the study of the relationship between the reprogramming of glucose metabolism and the signal of continued cancer proliferation.

Interplay Between Glucose Metabolism Reprogramming and Growth Suppressor

Mutations in oncogenes and tumor suppressors mediate the reprogramming of glucose metabolism, and cancer cells that undergo glucose metabolism reprogramming are able to escape growth inhibition. We can help customers analyze the relationship between the reprogramming of glucose metabolism and the evasion of growth inhibition, and find new targets for cancer therapy.

Interplay Between Glucose Metabolism Reprogramming and Cancer Cell Death

Reprogramming glucose metabolism is closely related to the programmed cell death of cancer cells. For example, tumor glucose metabolism reprogramming and lethal autophagy are mutually regulated. Inhibiting glycolysis can promote autophagy in cells, while highly expressed autophagy-related proteins can inhibit glycolysis, forming negative feedback. We are able to analyze the regulatory relationship between the reprogramming of glucose metabolism and cancer cell death resistance, and broaden the ideas for the combination therapy of cancer.

Interplay Between Glucose Metabolism Reprogramming and Replicative Immortality

Cancer cells achieve immortality without senescence restrictions or telomere protection. Numerous studies have shown that inhibition of glycolysis can induce premature senescence in cancer cells and has tumor suppressive effects. We are able to explore the new molecular mechanism of glucose metabolism regulators in the treatment of tumors by analyzing the relationship between glycolysis and cancer cell immortalization.

Interplay Between Glucose Metabolism Reprogramming and Angiogenesis

Blood vessels deliver oxygen and nutrients to the center of nutrient-deficient solid tumors, providing the energy necessary for cancer cells to grow. Inhibition of angiogenesis has also emerged as a clinical approach to cancer therapy. However, the regulatory role between glucose metabolism reprogramming and angiogenesis remains unclear. We are able to analyze the relationship between the reprogramming of glucose metabolism and angiogenesis to help customers gain a comprehensive understanding of the multi-stage development mechanism of tumors.

Interplay Between Glucose Metabolism Reprogramming and Invasion & Metastasis

Glucose metabolism in cancer cells is plastic and heterogeneous, and reprogramming of glucose metabolism enables cancer cells to survive in new environments. Accumulating evidence supports the regulation of glucose metabolism reprogramming on cancer cell invasion and metastasis. We are able to provide analysis services for the regulatory relationship between the reprogramming of glucose metabolism and the invasion and metastasis of cancer cells, providing support for a comprehensive understanding of cancer metabolic plasticity and heterogeneity.

Interplay Between Glucose Metabolism Reprogramming and Immune Escape

The reprogramming of glucose metabolism in cancer cells has a great impact on the tumor microenvironment, resulting in changes in metabolites and pH values in the tumor microenvironment, which further affects the function of immune cells, resulting in the immune escape of cancer cells. We are able to facilitate improvements in immunotherapy by analyzing the relationship between reprogramming glucose metabolism and cancer immune escape.

Interplay Between Glucose Metabolism Reprogramming and Genomic Instability

Glucose can be combined with proteins, lipids, and amino groups of nucleic acid molecules through non-enzymatic reactions to generate precursors of advanced glycation end products. Hyperglycemia leads to long-term accumulation of glycation end products, which eventually bind to glycation end product receptors on the cell membrane, causing cellular DNA damage and inducing tumorigenesis. We are able to analyze the interplay between genomic instability and reprogramming of glucose metabolism, providing important clues for the development of combination therapies for cancer.

Interplay Between Glucose Metabolism Reprogramming and Tumor-associated Inflammation

Disturbances in cancer glucose metabolism are accompanied by chronic inflammation, which in turn promotes tumor progression. We are able to provide an analysis of the regulatory relationship between the reprogramming of glucose metabolism and tumor-associated inflammation and promote the application of the analysis results to the clinical prevention, diagnosis, and treatment of cancer.

CD BioGlyco can provide analytics services on the interaction between glucose metabolism reprogramming and the top ten hallmarks of cancer, and provide customers with the best glucose metabolism reprogramming solutions. Our experienced teams of scientists, researchers, and technicians provide a fast turnaround, and high-quality services at competitive prices for worldwide customers. Our customers have direct access to our staff and prompt feedback on their inquiries. If you are interested in our services, please contact us for more details.

This service is for Research Use Only, not intended for any clinical use.

About Us

CD BioGlyco is a world-class biotechnology company with offices in many countries. Our products and services provide a viable option to what is otherwise available.

Important Links

Contact Us